Joanna K Tabor1,2, Brendan Ryu2,3, Daniel Schneider2, Daniel M Sciubba2, Ashwatha Narayana4, Avraham Zlochower5, Randy S D' Amico6. 1. SUNY Downstate College of Medicine, Brooklyn, NY, USA. 2. Department of Neurological Surgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA. 3. Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA. 4. Department of Radiation Oncology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA. 5. Department of Radiology, Lenox Hill Hospital, New York, NY, USA. 6. Department of Neurological Surgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA. rdamico8@northwell.edu.
Abstract
INTRODUCTION: Spinal myxopapillary ependymomas (SME) are rare WHO grade II neoplasms of the spinal cord. Despite their good prognosis, they have a high propensity for metastasis and recurrence, although the presentation of SME as multifocal is uncommon. CASE PRESENTATION: Here we describe a rare case of a 34-year-old man who presented with painful bilateral radiculopathy with sexual dysfunction and altered sensation with defecation. The patient also reported worsening weakness of bilateral lower extremities when climbing stairs. Biopsy results revealed multifocal SME in the lumbar and sacral spine that was treated with staged surgical resection and post-operative focal radiation therapy. DISCUSSION: We discuss and evaluate surgical resection and the role of postoperative radiotherapy for SME. We also review the literature surrounding multifocal SME presenting in adults.
INTRODUCTION: Spinal myxopapillary ependymomas (SME) are rare WHO grade II neoplasms of the spinal cord. Despite their good prognosis, they have a high propensity for metastasis and recurrence, although the presentation of SME as multifocal is uncommon. CASE PRESENTATION: Here we describe a rare case of a 34-year-old man who presented with painful bilateral radiculopathy with sexual dysfunction and altered sensation with defecation. The patient also reported worsening weakness of bilateral lower extremities when climbing stairs. Biopsy results revealed multifocal SME in the lumbar and sacral spine that was treated with staged surgical resection and post-operative focal radiation therapy. DISCUSSION: We discuss and evaluate surgical resection and the role of postoperative radiotherapy for SME. We also review the literature surrounding multifocal SME presenting in adults.
Authors: Zafer Orkun Toktaş; Mustafa Kemal Demir; Özlem Yapıcıer; Akın Akakın; Baran Yılmaz; Deniz Konya Journal: Spine J Date: 2015-08-04 Impact factor: 4.166
Authors: James E Bates; Carl R Peterson; Gabrielle A Yeaney; Kevin A Walter; Thomas Lundquist; Douglas Rosenzweig; Michael T Milano Journal: Rare Tumors Date: 2014-06-16