| Literature DB >> 35457370 |
Agata Pisula1, Agnieszka Sienicka1, Katarzyna Karina Pawlik1, Agnieszka Dobrowolska-Redo2, Joanna Kacperczyk-Bartnik2, Ewa Romejko-Wolniewicz2.
Abstract
Pregnant women are more susceptible to influenza virus infections due to the immunological and physiological changes in the course of pregnancy. Vaccination during pregnancy is a safe and effective method for protecting both the mothers and the infants from influenza and its complications. This study was conducted in order to determine the knowledge and attitudes of Polish pregnant women towards influenza vaccination during the COVID-19 pandemic. A questionnaire-based and self-administered study was carried out fully online and a total of 515 women participated. A total of 52% (n = 268) of surveyed women answered that vaccination against influenza during pregnancy was safe. However, only 21% (n = 108) were vaccinated against influenza during their current pregnancy and 17.5% (n = 90) intended to be vaccinated. The participants indicated many concerns about getting vaccinated during pregnancy, but also many benefits that come with the vaccination. General knowledge about influenza, its complications, and vaccination was quite high in the study group.Entities:
Keywords: COVID-19; influenza; pandemic; vaccination
Mesh:
Substances:
Year: 2022 PMID: 35457370 PMCID: PMC9031437 DOI: 10.3390/ijerph19084504
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Sociodemographic and obstetric characteristics of participants.
| Category (n = 515) | Variables | Frequency | Percentage |
|---|---|---|---|
| Age | 19–25 | 64 | 12.4 |
| 26–30 | 223 | 43.3 | |
| 31–35 | 164 | 31.8 | |
| 36–40 | 57 | 11.1 | |
| 41–43 | 7 | 1.4 | |
| Education | Primary | 2 | 0.4 |
| Vocational | 5 | 1.0 | |
| Secondary | 59 | 11.5 | |
| Univeristy students | 18 | 3.5 | |
| Higher | 431 | 83.7 | |
| Average income per household member | <1000 PLN | 15 | 2.9 |
| 1000–2000 PLN | 65 | 12.6 | |
| 2000–3000 PLN | 108 | 21.0 | |
| 3000–4000 PLN | 132 | 25.6 | |
| 4000–5000 PLN | 79 | 15.3 | |
| >5000 PLN | 116 | 22.5 | |
| Place of residence | Countryside | 104 | 20.2 |
| Small village (<50 k residents) | 68 | 13.2 | |
| Town (50–100 k residents) | 34 | 6.6 | |
| City (100–500 k) | 101 | 19.6 | |
| City (>500 k) | 209 | 40.6 | |
| Current relationship status | Single | 3 | 0.6 |
| Informal relationship | 96 | 18.6 | |
| Married | 414 | 80.4 | |
| Divorced | 2 | 0.4 | |
| Week of gestation | 1–13 | 60 | 11.7 |
| 14–27 | 196 | 38.1 | |
| 28–40 | 259 | 50.3 | |
| Number of pregnancies | 1 | 255 | 49.5 |
| 2 | 167 | 32.4 | |
| 3 | 63 | 12.2 | |
| 4+ | 30 | 5.8 | |
| Number of labours | 0 | 309 | 60.0 |
| 1 | 154 | 29.9 | |
| 2 | 41 | 8.0 | |
| 3+ | 11 | 2.1 | |
| Pregnancy | Single | 508 | 98.6 |
| Multiple | 7 | 1.4 | |
| Having children | Yes | 204 | 39.6 |
| No | 311 | 60.4 |
History of influenza and influenza vaccination status.
| Category (n = 515) | Variables | Frequency | Percentage |
|---|---|---|---|
| Have you ever had influenza? | Yes | 196 | 38.1 |
| No | 146 | 28.3 | |
| I don’t know | 173 | 33.6 | |
| Have you ever had an influenza test performed? | Yes | 34 | 6.6 |
| No | 464 | 90.1 | |
| I don’t know | 17 | 3.3 | |
| Have you ever been vaccinated against influenza? | Yes | 224 | 43.5 |
| No | 291 | 56.5 | |
| Have you been vaccinated against influenza during current pregnancy? | Yes | 108 | 21.0 |
| No, but I am going to | 90 | 17.5 | |
| No and I am not going to | 238 | 46.2 | |
| No and I do not know if I will get vaccinated | 79 | 15.3 |
Univariate regression analysis regarding influenza vaccination status.
| Category (n = 515) | ||||
|---|---|---|---|---|
| Age | 0.0374 | |||
| Education | 0.0743 | |||
| Average income per household member | 0.0001 | |||
| Place of residence | 0.0192 | |||
| Current relationship status | 0.3416 | |||
| 95% CI | ||||
| Variables | OR | Lower | Upper | |
| Age: 19–25 years old vs. | 0.0374 | |||
| 26–30y | 1.694 | 0.931 | 3.083 | 0.0843 |
| 31–35y | 2.045 | 1.103 | 3.794 | 0.0232 |
| 36–40y | 3.032 | 1.433 | 6.413 | 0.0037 |
| 41–43y | 3.158 | 0.644 | 15.487 | 0.1564 |
| Average income per household member: <1000 PLN vs. | 0.0001 | |||
| 1000–2000 PLN | 1.200 | 0.299 | 4.820 | 0.7972 |
| 2000–3000 PLN | 2.353 | 0.626 | 8.844 | 0.2053 |
| 3000–4000 PLN | 4.000 | 1.079 | 14.830 | 0.0381 |
| 4000–5000 PLN | 3.349 | 0.877 | 12.795 | 0.0772 |
| >5000 PLN | 4.923 | 1.319 | 18.375 | 0.0177 |
| Place of residence: Countryside vs. | 0.0192 | |||
| Small village (<50 k residents) | 1.430 | 0.765 | 2.670 | 0.2622 |
| Town (50–100 k residents) | 0.652 | 0.276 | 1.542 | 0.3302 |
| City (100–500 k) | 1.289 | 0.734 | 2.265 | 0.3773 |
| City (>500 k) | 1.882 | 1.159 | 3.056 | 0.0106 |
Multivariate analysis regarding influenza vaccination status.
| 95% CI | ||||
|---|---|---|---|---|
| Variables | OR | Lower | Upper | |
| Average income per household member: <1000 vs. | 0.009431 | |||
| 1000–2000 PLN | 1.400 | 0.339 | 5.791 | 0.642 |
| 2000–3000 PLN | 2.397 | 0.617 | 9.306 | 0.206 |
| 3000–4000 PLN | 3.949 | 1.030 | 15.146 | 0.045 |
| 4000–5000 PLN | 2.960 | 0.742 | 11.816 | 0.124 |
| >5000 PLN | 4.386 | 1.130 | 17.031 | 0.033 |
Univariate regression analysis regarding influenza vaccination status during current pregnancy.
| Category (n = 515) | ||||
|---|---|---|---|---|
| Age | 0.1736 | |||
| Education | 0.1204 | |||
| Average income per household member | 0.0000 | |||
| Place of residence | 0.0000 | |||
| Current relationship status | 0.4046 | |||
| 95% CI | ||||
| Variables | OR | Lower | Upper | |
| Average income per household member: <1000 PLN vs. | 0.0000 | |||
| 1000–2000 PLN | 0.727 | 0.173 | 3.049 | 0.6632 |
| 2000–3000 PLN | 1.610 | 0.425 | 6.102 | 0.4833 |
| 3000–4000 PLN | 2.947 | 0.794 | 10.939 | 0.1062 |
| 4000–5000 PLN | 3.022 | 0.790 | 11.557 | 0.1061 |
| >5000 PLN | 4.923 | 1.319 | 18.375 | 0.0177 |
| Place of residence: Countryside vs. | 0.0000 | |||
| Small village (<50 k residents) | 1.322 | 0.683 | 2.558 | 0.4076 |
| Town (50–100 k residents) | 0.162 | 0.036 | 0.718 | 0.0166 |
| City (100–500 k) | 1.255 | 0.691 | 2.280 | 0.4559 |
| City (>500 k) | 2.959 | 1.781 | 4.918 | 0.0000 |
Multivariate analysis regarding influenza vaccination status during current pregnancy.
| 95% CI | ||||
|---|---|---|---|---|
| Variables | OR | Lower | Upper | |
| Average income per household member: <1000 PLN vs. | 0.001022 | |||
| >5000 PLN | 3.896 | 1.001 | 15.170 | 0.050 |
| Place of residence: Countryside vs. | 0.000284 | |||
| Town (50–100 k residents) | 0.144 | 0.032 | 0.651 | 0.012 |
| City (>500 k) | 2.126 | 1.237 | 3.654 | 0.006 |
Figure 1Respondents’ knowledge about risk groups for severe influenza.
Figure 2Respondents’ knowledge about influenza treatment.
Participants’ knowledge about the influenza complications in pregnancy.
| Complications (n = 515) | Frequency | Percentage |
|---|---|---|
| Pneumonia | 265 | 51.5 |
| Premature delivery | 237 | 46.0 |
| Acute respiratory failure | 233 | 45.2 |
| Cardiopulmonary arrest | 195 | 37.9 |
| Spontaneous abortion | 172 | 33.4 |
| Low birth weight | 122 | 23.7 |
| Intrauterine fetal demise | 121 | 23.5 |
| Fetal tachyarrhythmia | 74 | 14.4 |
| Have not heard about any complications | 141 | 27.4 |
Participants’ knowledge about the influenza complications in infants.
| Complications (n = 515) | Frequency | Percentage |
|---|---|---|
| Pneumonia | 243 | 47.2 |
| Respiratory failure | 215 | 41.7 |
| Myocarditis | 197 | 38.3 |
| Bronchitis | 175 | 34.0 |
| Meningitis | 123 | 23.9 |
| Sepsis | 107 | 20.8 |
| Have not heard about any complications | 195 | 37.9 |
Univariate regression analysis regarding COVID-19 vaccination status.
| Category (n = 515) | ||||
|---|---|---|---|---|
| Age | 0.1281 | |||
| Education | 0.0001 | |||
| Average income per household member | 0.0000 | |||
| Place of residence | 0.0000 | |||
| Current relationship status | 0.2405 | |||
| 95% CI | ||||
| Variables | OR | Lower | Upper | |
| Education: Primary and Vocational vs. | 0.0001 | |||
| Secondary | 1.714 | 0.307 | 9.575 | 0.5391 |
| University Students | 3.125 | 0.474 | 20.584 | 0.2361 |
| Higher | 5.423 | 1.039 | 28.304 | 0.0449 |
| Average income per household member: <1000 PLN vs. | 0.0000 | |||
| 1000–2000 PLN | 1.506 | 0.430 | 5.268 | 0.5216 |
| 2000–3000 PLN | 3.437 | 1.029 | 11.478 | 0.0447 |
| 3000–4000 PLN | 6.558 | 1.967 | 21.858 | 0.0022 |
| 4000–5000 PLN | 8.112 | 2.320 | 28.364 | 0.0010 |
| >5000 PLN | 10.524 | 3.083 | 36.044 | 0.0002 |
| Place of residence: Countryside vs. | 0.0000 | |||
| Small village (<50 k residents) | 1.510 | 0.815 | 2.794 | 0.1900 |
| Town (50–100 k residents) | 1.122 | 0.517 | 2.436 | 0.7701 |
| City (100–500 k) | 2.117 | 1.206 | 3.714 | 0.0090 |
| City (>500 k) | 3.741 | 2.264 | 6.183 | 0.0000 |
Multivariate analysis regarding COVID-19 vaccination status.
| 95% CI | ||||
|---|---|---|---|---|
| Variables | OR | Lower | Upper | |
| Average income per household member: <1000 PLN vs. | 0.000314 | |||
| 3000–4000 PLN | 4.484 | 1.288 | 15.605 | 0.018 |
| 4000–5000 PLN | 4.693 | 1.272 | 17.311 | 0.020 |
| >5000 PLN | 6.273 | 1.745 | 22.553 | 0.005 |
| Place of residence: Countryside vs. | 0.027920 | |||
| City (>500 k) | 2.407 | 1.396 | 4.148 | 0.002 |
Association between COVID-19 and influenza vaccine uptake during pregnancy.
| Vaccination against Influenza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Vaccination against COVID-19 | Yes | No, but I am going to | No and I am not going to | No and I do not know if I will get vaccinated | Spearman rank coefficient | ||||
| n | % | n | % | n | % | n | % | ||
| Yes, before pregnancy | 46 | 8.9 | 55 | 10.7 | 34 | 6.6 | 19 | 3.7 | 0.505952 |
| Yes, during pregnancy | 54 | 10.5 | 29 | 5.6 | 36 | 7.0 | 26 | 5.0 | |
| No, but I am going to | 3 | 0.6 | 1 | 0.2 | 22 | 4.3 | 6 | 1.2 | |
| No and I am not going to | 1 | 0.2 | 1 | 0.2 | 111 | 21.6 | 7 | 1.4 | |
| No and I do not know if I will get vaccinated | 4 | 0.8 | 4 | 0.8 | 35 | 6.8 | 21 | 4.1 | |