Literature DB >> 35451456

SimPlot ++: a Python application for representing sequence similarity and detecting recombination.

Stéphane Samson1, Étienne Lord2, Vladimir Makarenkov1.   

Abstract

MOTIVATION: Accurate detection of sequence similarity and homologous recombination are essential parts of many evolutionary analyses.
RESULTS: We have developed SimPlot ++, an open-source multiplatform application implemented in Python, which can be used to produce publication quality sequence similarity plots using 63 nucleotide and 20 amino acid distance models, to detect intergenic and intragenic recombination events using Φ, Max-χ2, NSS or proportion tests, and to generate and analyze interactive sequence similarity networks. SimPlot ++ supports multicore data processing and provides useful distance calculability diagnostics. AVAILABILITY: SimPlot ++ is freely available on GitHub at: https://github.com/Stephane-S/Simplot_PlusPlus, as both an executable file (for Windows) and Python scripts (for Windows/Linux/MacOS).
© The Author(s) (2022). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Year:  2022        PMID: 35451456     DOI: 10.1093/bioinformatics/btac287

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


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