Literature DB >> 3545109

Effect of a stable prostacyclin analogue on canine renal allograft rejection.

M Tobimatsu, Y Ueda, K Toyoda, S Saito, K Konomi.   

Abstract

The effect of OP-41483 (Ono Pharmaceutical Co., Osaka, Japan), a stable prostacyclin analogue, on canine renal allograft rejection was investigated. Administration for 4 days after transplantation significantly increased renal cortical blood flow and urine output when compared with untreated dogs with renal allografts. Serum creatinine levels remained relatively low during postoperative days 1-4. Mean animal survival time was prolonged. Vascular lesions and mononuclear cell infiltration were greatly diminished in biopsy specimens removed on day 4. This stable prostacyclin analogue provided a degree of protection against canine renal allograft rejection.

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Year:  1987        PMID： 3545109      PMCID： PMC1492822          DOI： 10.1097/00000658-198702000-00016

Source DB:  PubMed          Journal:  Ann Surg        ISSN： 0003-4932            Impact factor:   12.969


  18 in total

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Authors:  S Moncada; J R Vane
Journal:  Pharmacol Rev       Date:  1978-09       Impact factor: 25.468

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Authors:  K AUKLAND; B F BOWER; R W BERLINER
Journal:  Circ Res       Date:  1964-02       Impact factor: 17.367

3.  Indium-labelled autologous platelets as diagnostic aid after renal transplantation.

Authors:  N Smith; S Chandler; R J Hawker; L M Hawker; A D Barnes
Journal:  Lancet       Date:  1979-12-08       Impact factor: 79.321

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Authors:  A B Retik; N K Hollenberg; S M Rosen; J P Merrill; J E Murray
Journal:  Surg Gynecol Obstet       Date:  1967-05

5.  A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation.

Authors:  S Moncada; R J Gryglewski; S Bunting; J R Vane
Journal:  Prostaglandins       Date:  1976-11

6.  An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation.

Authors:  S Moncada; R Gryglewski; S Bunting; J R Vane
Journal:  Nature       Date:  1976-10-21       Impact factor: 49.962

7.  Experimental assessment of prostacyclin in the harvesting of kidneys for transplantation.

Authors:  A R Mundy; M Bewick; S Moncada; J R Vane
Journal:  Transplantation       Date:  1980-10       Impact factor: 4.939

8.  Prostaglandin modulation of development of cell-mediated immunity in culture.

Authors:  K H Leung; E Mihich
Journal:  Nature       Date:  1980-12-11       Impact factor: 49.962

9.  Enhanced prostacyclin synthesis in acute human kidney transplant rejection.

Authors:  C Leithner; H Sinzinger; K Silberbauer; A Wolf; H K Stummvoll; W Pinggera
Journal:  Proc Eur Dial Transplant Assoc       Date:  1980

10.  Human arterial and venous tissues generate prostacyclin (prostaglandin x), a potent inhibitor of platelet aggregation.

Authors:  S Moncada; E A Higgs; J R Vane
Journal:  Lancet       Date:  1977-01-01       Impact factor: 79.321
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  2 in total

1.  Evaluation of Renal Blood Flow in Dogs during Short-Term Human-Dose Epoprostenol Administration Using Pulsed Doppler and Contrast-Enhanced Ultrasonography.

Authors:  Kiwamu Hanazono; Takaharu Itami; Ikuto Hayasaka; Kenjiro Miyoshi; Ai Hori; Keiko Kato; Daiji Endoh
Journal:  Animals (Basel)       Date:  2022-05-04       Impact factor: 3.231

2.  Treprostinil, a prostacyclin analog, ameliorates renal ischemia-reperfusion injury: preclinical studies in a rat model of acute kidney injury.

Authors:  Meiwen Ding; Evelyn Tolbert; Mark Birkenbach; Fatemeh Akhlaghi; Reginald Gohh; Nisanne S Ghonem
Journal:  Nephrol Dial Transplant       Date:  2021-01-25       Impact factor: 5.992
  2 in total

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