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Literature DB >> 35450139

Diagnosis and Treatment of Kaposi's Sarcoma.

Abstract

Kaposi's sarcoma is the most common tumor associated with human immunodeficiency virus infection and is found in homosexual and bisexual men, injection drug users, and hemophiliacs. Its incidence has declined over the past 20 years, but it is not yet curable. Evaluation, biopsy, workup, and staging are essential to providing proper treatment. Immune system impairment is the single most important predictor of survival.

Entities: Chemical

Year: 2001 PMID： 35450139 PMCID： PMC9020379

Source DB: PubMed Journal: Resid Staff Physician ISSN： 0034-5555

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References

21 in total

1. Human herpesvirus 8 latent-state gene expression and apoptosis in Kaposi's sarcoma lesions.

Authors: G S Hayward
Journal: J Natl Cancer Inst Date: 1999-10-20 Impact factor: 13.506

2. Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma.

Authors: J D Moore; B J Dezube; P Gill; X J Zhou; E P Acosta; J P Sommadossi
Journal: Cancer Chemother Pharmacol Date: 2000 Impact factor: 3.333

3. Oral Kaposi's sarcoma in acquired immunodeficiency syndrome. Review of management and report of the efficacy of intralesional vinblastine.

Authors: J B Epstein; F Lozada-Nur; W A McLeod; J Spinelli
Journal: Cancer Date: 1989-12-15 Impact factor: 6.860

4. AIDS-related Kaposi's sarcoma: prospective validation of the AIDS Clinical Trials Group staging classification. AIDS Clinical Trials Group Oncology Committee.

Authors: S E Krown; M A Testa; J Huang
Journal: J Clin Oncol Date: 1997-09 Impact factor: 44.544

5. Heterogeneity of epidemic Kaposi's sarcoma. Implications for therapy.

Authors: R T Mitsuyasu; J M Taylor; J Glaspy; J L Fahey
Journal: Cancer Date: 1986-04-15 Impact factor: 6.860

6. Treatment of Kaposi's sarcoma in acquired immunodeficiency syndrome with an alternating vincristine-vinblastine regimen.

Authors: L Kaplan; D Abrams; P Volberding
Journal: Cancer Treat Rep Date: 1986-09

Diagnosis and Treatment of Kaposi's Sarcoma.

1. Human herpesvirus 8 latent-state gene expression and apoptosis in Kaposi's sarcoma lesions.

2. Phase I dose escalation pharmacokinetics of O-(chloroacetylcarbamoyl) fumagillol (TNP-470) and its metabolites in AIDS patients with Kaposi's sarcoma.

3. Oral Kaposi's sarcoma in acquired immunodeficiency syndrome. Review of management and report of the efficacy of intralesional vinblastine.

4. AIDS-related Kaposi's sarcoma: prospective validation of the AIDS Clinical Trials Group staging classification. AIDS Clinical Trials Group Oncology Committee.

5. Heterogeneity of epidemic Kaposi's sarcoma. Implications for therapy.

6. Treatment of Kaposi's sarcoma in acquired immunodeficiency syndrome with an alternating vincristine-vinblastine regimen.

7. Activity of thalidomide in AIDS-related Kaposi's sarcoma.

8. Detection of herpesvirus-like DNA sequences in Kaposi's sarcoma in patients with and those without HIV infection.

9. Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro.

10. Treatment of epidemic Kaposi's sarcoma with etoposide or a combination of doxorubicin, bleomycin, and vinblastine.