Literature DB >> 35440968

Type 2 Diabetes Mellitus with HbJ trait: A management conundrum.

Wan Natrah Wan Yaacob1, Lili Husniati Yaacob2, Nani Draman3.   

Abstract

Optimal glycaemic control is crucial in patients with diabetes mellitus (DM) to avoid episodes of hypoglycaemia and both micro- and macrovascular complications. Diabetic control relies mainly on the evaluation of haemoglobin A1c (HbA1c), which is unfortunately unreliable in patients with haemoglobinopathies. This case report describes a patient with type 2 DM and haemoglobin J (HbJ) trait, which resulted in erratic HbA1c values throughout her follow-up. Other approaches, such as self-blood glucose monitoring, are needed to evaluate glycaemic control instead of relying on HbA1c alone to guide the management DM in these patients. © Academy of Family Physicians of Malaysia.

Entities:  

Keywords:  HbA1c; HbJ trait; haemoglobinopathy

Year:  2022        PMID: 35440968      PMCID: PMC9004435          DOI: 10.51866/cr1288

Source DB:  PubMed          Journal:  Malays Fam Physician        ISSN: 1985-2274


  5 in total

1.  Falsely low HbA1c value due to a rare variant of hemoglobin J-Baltimore.

Authors:  Ossama Barakat; S T Murali Krishnan; Ketan Dhatariya
Journal:  Prim Care Diabetes       Date:  2008-07-09       Impact factor: 2.459

2.  P3 Fraction: Effect on HbA1c Values by HPLC.

Authors:  Mrinal Gupta; Mohit Thalquotra; Pragna Rao
Journal:  J Clin Diagn Res       Date:  2016-09-01

Review 3.  Pitfalls in hemoglobin A1c measurement: when results may be misleading.

Authors:  Michael S Radin
Journal:  J Gen Intern Med       Date:  2013-09-04       Impact factor: 5.128

4.  Glycemic monitoring in diabetics with sickle cell plus beta-thalassemia hemoglobinopathy.

Authors:  Sheri M Kosecki; Philip T Rodgers; Martha B Adams
Journal:  Ann Pharmacother       Date:  2005-08-02       Impact factor: 3.154

5.  Conundrum of elevated HbA1C and hypoglycemia-a rare cause.

Authors:  Sudip Nanda; Shree Gopal Sharma; Surya Prakash Bhatt; John Pamula; Mohammad I Arastu
Journal:  Am J Med Sci       Date:  2008-05       Impact factor: 2.378

  5 in total

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