Literature DB >> 35440726

Targeting the gut and tumor microbiota in cancer.

Elizabeth M Park1,2, Manoj Chelvanambi2, Neal Bhutiani2, Guido Kroemer3,4,5,6, Laurence Zitvogel7,8,9,10, Jennifer A Wargo11,12.   

Abstract

Microorganisms within the gut and other niches may contribute to carcinogenesis, as well as shaping cancer immunosurveillance and response to immunotherapy. Our understanding of the complex relationship between different host-intrinsic microorganisms, as well as the multifaceted mechanisms by which they influence health and disease, has grown tremendously-hastening development of novel therapeutic strategies that target the microbiota to improve treatment outcomes in cancer. Accordingly, the evaluation of a patient's microbial composition and function and its subsequent targeted modulation represent key elements of future multidisciplinary and precision-medicine approaches. In this Review, we outline the current state of research toward harnessing the microbiome to better prevent and treat cancer.
© 2022. Springer Nature America, Inc.

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Year:  2022        PMID： 35440726     DOI： 10.1038/s41591-022-01779-2

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   87.241


  221 in total

1.  Nivolumab in previously untreated melanoma without BRAF mutation.

Authors:  Caroline Robert; Georgina V Long; Benjamin Brady; Caroline Dutriaux; Michele Maio; Laurent Mortier; Jessica C Hassel; Piotr Rutkowski; Catriona McNeil; Ewa Kalinka-Warzocha; Kerry J Savage; Micaela M Hernberg; Celeste Lebbé; Julie Charles; Catalin Mihalcioiu; Vanna Chiarion-Sileni; Cornelia Mauch; Francesco Cognetti; Ana Arance; Henrik Schmidt; Dirk Schadendorf; Helen Gogas; Lotta Lundgren-Eriksson; Christine Horak; Brian Sharkey; Ian M Waxman; Victoria Atkinson; Paolo A Ascierto
Journal:  N Engl J Med       Date:  2014-11-16       Impact factor: 91.245

Review 2.  Microbes in gastrointestinal health and disease.

Authors:  Andrew S Neish
Journal:  Gastroenterology       Date:  2008-11-19       Impact factor: 22.682

3.  Evidence for early life in Earth's oldest hydrothermal vent precipitates.

Authors:  Matthew S Dodd; Dominic Papineau; Tor Grenne; John F Slack; Martin Rittner; Franco Pirajno; Jonathan O'Neil; Crispin T S Little
Journal:  Nature       Date:  2017-03-01       Impact factor: 49.962

4.  Influence of the microbiota on host physiology - moving beyond the gut.

Authors:  Kim E Barrett; Gary D Wu
Journal:  J Physiol       Date:  2017-01-15       Impact factor: 5.182

5.  Pembrolizumab plus Axitinib versus Sunitinib for Advanced Renal-Cell Carcinoma.

Authors:  Brian I Rini; Elizabeth R Plimack; Viktor Stus; Rustem Gafanov; Robert Hawkins; Dmitry Nosov; Frédéric Pouliot; Boris Alekseev; Denis Soulières; Bohuslav Melichar; Ihor Vynnychenko; Anna Kryzhanivska; Igor Bondarenko; Sergio J Azevedo; Delphine Borchiellini; Cezary Szczylik; Maurice Markus; Raymond S McDermott; Jens Bedke; Sophie Tartas; Yen-Hwa Chang; Satoshi Tamada; Qiong Shou; Rodolfo F Perini; Mei Chen; Michael B Atkins; Thomas Powles
Journal:  N Engl J Med       Date:  2019-02-16       Impact factor: 91.245

6.  The origin of atmospheric oxygen on Earth: the innovation of oxygenic photosynthesis.

Authors:  G C Dismukes; V V Klimov; S V Baranov; Y N Kozlov; J DasGupta; A Tyryshkin
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-27       Impact factor: 11.205

7.  Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair-Deficient/Microsatellite Instability-High Metastatic Colorectal Cancer.

Authors:  Michael J Overman; Sara Lonardi; Ka Yeung Mark Wong; Heinz-Josef Lenz; Fabio Gelsomino; Massimo Aglietta; Michael A Morse; Eric Van Cutsem; Ray McDermott; Andrew Hill; Michael B Sawyer; Alain Hendlisz; Bart Neyns; Magali Svrcek; Rebecca A Moss; Jean-Marie Ledeine; Z Alexander Cao; Shital Kamble; Scott Kopetz; Thierry André
Journal:  J Clin Oncol       Date:  2018-01-20       Impact factor: 44.544

8.  Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial.

Authors:  Jeffrey S Weber; Sandra P D'Angelo; David Minor; F Stephen Hodi; Ralf Gutzmer; Bart Neyns; Christoph Hoeller; Nikhil I Khushalani; Wilson H Miller; Christopher D Lao; Gerald P Linette; Luc Thomas; Paul Lorigan; Kenneth F Grossmann; Jessica C Hassel; Michele Maio; Mario Sznol; Paolo A Ascierto; Peter Mohr; Bartosz Chmielowski; Alan Bryce; Inge M Svane; Jean-Jacques Grob; Angela M Krackhardt; Christine Horak; Alexandre Lambert; Arvin S Yang; James Larkin
Journal:  Lancet Oncol       Date:  2015-03-18       Impact factor: 41.316

9.  Pembrolizumab versus Chemotherapy for PD-L1-Positive Non-Small-Cell Lung Cancer.

Authors:  Martin Reck; Delvys Rodríguez-Abreu; Andrew G Robinson; Rina Hui; Tibor Csőszi; Andrea Fülöp; Maya Gottfried; Nir Peled; Ali Tafreshi; Sinead Cuffe; Mary O'Brien; Suman Rao; Katsuyuki Hotta; Melanie A Leiby; Gregory M Lubiniecki; Yue Shentu; Reshma Rangwala; Julie R Brahmer
Journal:  N Engl J Med       Date:  2016-10-08       Impact factor: 91.245

Review 10.  Role of the microbiome in human development.

Authors:  Maria Gloria Dominguez-Bello; Filipa Godoy-Vitorino; Rob Knight; Martin J Blaser
Journal:  Gut       Date:  2019-01-22       Impact factor: 23.059
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  10 in total

1.  Diet and Exercise in Cancer Metabolism.

Authors:  Jason W Locasale
Journal:  Cancer Discov       Date:  2022-10-05       Impact factor: 38.272

2.  Commentary: The Modulation of Chaihu Shugan Formula on Microbiota Composition in the Simulator of the Human Intestinal Microbial Ecosystem Technology Platform and Its Influence on Gut Barrier and Intestinal Immunity in Caco-2/THP1-Blue™ Cell Co-Culture Model.

Authors:  Yang Yu; Cun Liu; Jingyang Liu; Jing Zhuang; Changgang Sun
Journal:  Front Pharmacol       Date:  2022-06-01       Impact factor: 5.988

Review 3.  Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis.

Authors:  Xiaomin Su; Yunhuan Gao; Rongcun Yang
Journal:  Cells       Date:  2022-07-25       Impact factor: 7.666

Review 4.  Regulation of CD4+ and CD8+ T Cell Biology by Short-Chain Fatty Acids and Its Relevance for Autoimmune Pathology.

Authors:  Carmen Schiweck; Sharmili Edwin Thanarajah; Mareike Aichholzer; Silke Matura; Andreas Reif; Elske Vrieze; Andreas Weigert; Alexander Visekruna
Journal:  Int J Mol Sci       Date:  2022-07-27       Impact factor: 6.208

5.  Association of Intratumoral Microbiota With Prognosis in Patients With Nasopharyngeal Carcinoma From 2 Hospitals in China.

Authors:  Han Qiao; Xi-Rong Tan; Hui Li; Jun-Yan Li; Xiao-Zhong Chen; Ying-Qin Li; Wen-Fei Li; Ling-Long Tang; Guan-Qun Zhou; Yuan Zhang; Ye-Lin Liang; Qing-Mei He; Yin Zhao; Sheng-Yan Huang; Sha Gong; Qian Li; Ming-Liang Ye; Kai-Lin Chen; Ying Sun; Jun Ma; Na Liu
Journal:  JAMA Oncol       Date:  2022-09-01       Impact factor: 33.006

6.  Dysbiosis of human tumor microbiome and aberrant residence of Actinomyces in tumor-associated fibroblasts in young-onset colorectal cancer.

Authors:  Zhuoqing Xu; Zeping Lv; Fangqian Chen; Yuchen Zhang; Zifeng Xu; Jianting Huo; Wangyi Liu; Suyue Yu; Abudumaimaitijiang Tuersun; Jingkun Zhao; Yaping Zong; Xiaonan Shen; Wenqing Feng; Aiguo Lu
Journal:  Front Immunol       Date:  2022-09-02       Impact factor: 8.786

Review 7.  Effects and Mechanisms of Curcumin for the Prevention and Management of Cancers: An Updated Review.

Authors:  Zhi-Jun Yang; Si-Yu Huang; Dan-Dan Zhou; Ruo-Gu Xiong; Cai-Ning Zhao; Ai-Ping Fang; Yun-Jian Zhang; Hua-Bin Li; Hui-Lian Zhu
Journal:  Antioxidants (Basel)       Date:  2022-07-28

Review 8.  From Intestinal Epithelial Homeostasis to Colorectal Cancer: Autophagy Regulation in Cellular Stress.

Authors:  Qiuluo Liu; Yan Chen; Li Zhou; Haining Chen; Zongguang Zhou
Journal:  Antioxidants (Basel)       Date:  2022-06-30

9.  Global research trends on the links between gut microbiota and cancer immunotherapy: A bibliometric analysis (2012-2021).

Authors:  Shanshan Yang; Suya Zhao; Yixiang Ye; Liqun Jia; Yanni Lou
Journal:  Front Immunol       Date:  2022-08-24       Impact factor: 8.786

10.  Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes.

Authors:  Casey T Finnicum; Zahraa Rahal; Maya Hassane; Warapen Treekitkarnmongkol; Ansam Sinjab; Rhiannon Morris; Yuejiang Liu; Elizabeth L Tang; Sarah Viet; Jason L Petersen; Philip L Lorenzi; Lin Tan; Joseph Petrosino; Kristi L Hoffman; Junya Fujimoto; Seyed Javad Moghaddam; Humam Kadara
Journal:  Int J Mol Sci       Date:  2022-09-18       Impact factor: 6.208
  10 in total

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