Literature DB >> 3543748

Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain.

K J Anderson, D T Monaghan, C B Cangro, M A Namboodiri, J H Neale, C W Cotman.   

Abstract

N-acetylaspartylglutamate (NAAG) was detected immunohistochemically in the rat brain using an antiserum which recognizes carbodiimide-fixed NAAG. NAAG-like immunoreactivity is described in 5 areas of the brain; olfactory bulb, septal nuclear area, lateral geniculate nucleus, superior colliculus and the entorhinal cortex/hippocampal formation. Mitral cells of the olfactory bulb and neurons concentrated in the medial septum were densely immunostained. A dense population of immunoreactive puncta was found in the superior colliculus and lateral geniculate nucleus (LGN). The LGN also contained immunoreactive neurons. The entorhinal cortex contained numerous immunoreactive cells in layers II-III while the hippocampus had few neurons that were NAAG-positive.

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Year:  1986        PMID: 3543748     DOI: 10.1016/0304-3940(86)90610-5

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  8 in total

1.  Glutamate-like immunoreactivity revealed in rat olfactory bulb, hippocampus and cerebellum by monoclonal antibody and sensitive staining method.

Authors:  C J Liu; P Grandes; C Matute; M Cuénod; P Streit
Journal:  Histochemistry       Date:  1989

Review 2.  Advances in understanding the peptide neurotransmitter NAAG and appearance of a new member of the NAAG neuropeptide family.

Authors:  Joseph H Neale; Rafal T Olszewski; Daiying Zuo; Karolina J Janczura; Caterina P Profaci; Kaleen M Lavin; John C Madore; Tomasz Bzdega
Journal:  J Neurochem       Date:  2011-07-01       Impact factor: 5.372

Review 3.  Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis.

Authors:  P J Shaw; C J Eggett
Journal:  J Neurol       Date:  2000-03       Impact factor: 4.849

4.  GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism.

Authors:  Emilio R Garrido Sanabria; Krystyna M Wozniak; Barbara S Slusher; Asaf Keller
Journal:  J Neurophysiol       Date:  2003-08-13       Impact factor: 2.714

5.  Odor-induced increases in c-fos mRNA expression reveal an anatomical "unit" for odor processing in olfactory bulb.

Authors:  K M Guthrie; A J Anderson; M Leon; C Gall
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-15       Impact factor: 11.205

6.  Excitatory amino acid receptors and synaptic transmission in the rat ventrobasal thalamus.

Authors:  T E Salt
Journal:  J Physiol       Date:  1987-10       Impact factor: 5.182

7.  Evidence of NAAG-family tripeptide NAAG2 in the Drosophila nervous system.

Authors:  Emily M Kozik; Elaine M Marzluff; Clark A Lindgren
Journal:  J Neurochem       Date:  2020-09-21       Impact factor: 5.546

8.  Dendritic Localization and Exocytosis of NAAG in the Rat Hippocampus.

Authors:  K Nordengen; C Morland; B S Slusher; V Gundersen
Journal:  Cereb Cortex       Date:  2020-03-14       Impact factor: 5.357

  8 in total

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