Literature DB >> 3543689

A cytosolic protein contains a cryptic mitochondrial targeting signal.

E C Hurt, G Schatz.   

Abstract

Cytosolic dihydrofolate reductase from mouse contains a cryptic mitochondrial targeting sequence. If this sequence is attached to the amino terminus of 'passenger' proteins which by themselves cannot enter mitochondria, the resulting fusion proteins are transported into yeast mitochondria.

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Year:  1987        PMID： 3543689     DOI： 10.1038/325499a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  28 in total

1.  Mitochondrial protein import: recognition of internal import signals of BCS1 by the TOM complex.

Authors:  Tincuta Stan; Jan Brix; Jens Schneider-Mergener; Nikolaus Pfanner; Walter Neupert; Doron Rapaport
Journal:  Mol Cell Biol       Date:  2003-04       Impact factor: 4.272

Review 2.  Mitochondrial protein import.

Authors:  V Geli; B Glick
Journal:  J Bioenerg Biomembr       Date:  1990-12       Impact factor: 2.945

Review 3.  Intracellular traffic of newly synthesized proteins. Current understanding and future prospects.

Authors:  V R Lingappa
Journal:  J Clin Invest       Date:  1989-03       Impact factor: 14.808

Review 4.  Targeting proteins to mitochondria: a current overview.

Authors:  L A Glover; J G Lindsay
Journal:  Biochem J       Date:  1992-06-15       Impact factor: 3.857

Review 5.  Proteolysis in protein import and export: signal peptide processing in eu- and prokaryotes.

Authors:  M Müller
Journal:  Experientia       Date:  1992-02-15

6.  The N-terminal (pre-S2) domain of a hepatitis B virus surface glycoprotein is translocated across membranes by downstream signal sequences.

Authors:  B E Eble; V R Lingappa; D Ganem
Journal:  J Virol       Date:  1990-03       Impact factor: 5.103

7.  Recent developments in chloroplast protein transport.

Authors:  M L Mishkind; S E Scioli
Journal:  Photosynth Res       Date:  1988-01       Impact factor: 3.573

Review 8.  Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process.

Authors:  M H Saier; P K Werner; M Müller
Journal:  Microbiol Rev       Date:  1989-09

9.  Cloning and cDNA sequence of the dihydrolipoamide dehydrogenase component human alpha-ketoacid dehydrogenase complexes.

Authors:  G Pons; C Raefsky-Estrin; D J Carothers; R A Pepin; A A Javed; B W Jesse; M K Ganapathi; D Samols; M S Patel
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

Review 10.  Protein transport and compartmentation in yeast.

Authors:  J Horák
Journal:  Folia Microbiol (Praha)       Date:  1991       Impact factor: 2.099
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