Literature DB >> 3543670

Lipid alterations induced by nifurtimox in Trypanosoma cruzi.

E Barreto-Bergter, L Hogge, F Steele da Cruz.   

Abstract

The influence of growth in the presence of nifurtimox on total lipids of Trypanosoma cruzi epimastigotes was determined. Nifurtimox-treated organisms showed greater amounts of unsaturated fatty acids as compared with control cells. 18:2 was the major component in the total esterified lipid fraction. Similar results were observed on the free fatty acid composition as detected by trimethylsilyl derivatization of the total lipids.

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Year:  1986        PMID: 3543670     DOI: 10.1016/0166-6851(86)90127-1

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN: 0166-6851            Impact factor:   1.759


  2 in total

Review 1.  Advances in preclinical approaches to Chagas disease drug discovery.

Authors:  Fernando Villalta; Girish Rachakonda
Journal:  Expert Opin Drug Discov       Date:  2019-08-14       Impact factor: 6.098

2.  The N-myristoylome of Trypanosoma cruzi.

Authors:  Adam J Roberts; Alan H Fairlamb
Journal:  Sci Rep       Date:  2016-08-05       Impact factor: 4.379

  2 in total

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