Marine fish oils: role in prevention of coronary artery disease.

Since the early 1970s, investigators have been interested in the relationship between dietary marine fish oils and plasma lipoproteins. Previous studies have shown that consumption of a diet rich in marine fatty acids results in altered lipid profiles, prolonged bleeding times, reduced platelet aggregation, and decreased blood pressure, but the precise mechanisms of action must be examined further. These findings, however, have led to the conclusion that dietary marine fish oils may be of benefit in the prevention of coronary artery disease. Before specific recommendations can be made about their general use, further studies of their long-term efficacy and toxicity must be conducted.