| Literature DB >> 35430847 |
Jiajia Zhang1, Yuanhua Qiao1, Yan Zhang1.
Abstract
In this paper, an improved COVID-19 model is given to investigate the influence of treatment and media awareness, and a non-linear saturated treatment function is introduced in the model to lay stress on the limited medical conditions. Equilibrium points and their stability are explored. Basic reproduction number is calculated, and the global stability of the equilibrium point is studied under the given conditions. An object function is introduced to explore the optimal control strategy concerning treatment and media awareness. The existence, characterization and uniqueness of optimal solution are studied. Several numerical simulations are given to verify the analysis results. Finally, discussion on treatment and media awareness is given for prevention and treatment of COVID-19.Entities:
Keywords: COVID-19 ; epidemic model ; globally stable ; optimal control ; sensitivity analysis
Mesh:
Year: 2022 PMID: 35430847 DOI: 10.3934/mbe.2022230
Source DB: PubMed Journal: Math Biosci Eng ISSN: 1547-1063 Impact factor: 2.080