Literature DB >> 35427068

Retraction: Long noncoding RNA DLEU1 promotes cell proliferation and migration of Wilms tumor through the miR-300/HOXC8 axis.

Laura Fisher1.   

Abstract

[This retracts the article DOI: 10.1039/C9RA07215B.]. This journal is © The Royal Society of Chemistry.

Entities:  

Year:  2021        PMID: 35427068      PMCID: PMC8694719          DOI: 10.1039/d1ra90051j

Source DB:  PubMed          Journal:  RSC Adv        ISSN: 2046-2069            Impact factor:   3.361


The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to concerns with the reliability of the data. The paper was analysed by experts who fact-checked the identities of the described nucleotide sequence reagents,[1] and found errors with the following nucleotide sequence reagents reported in the article: HOXC8 forward and reverse primers, and miR-300 reverse primer. The HOXC8 primers would not be expected to bind to nor amplify the target sequence, and therefore the results in Fig. 6 are unreliable. The reported miR-300 reverse primer is non-targeting and does not bind to miR-300, therefore the results shown in Fig. 4 and 5 are not reliable. Given the significance of the concerns about the validity of the data, the findings presented in this paper are not reliable. The authors have been informed but have not responded to any correspondence regarding the retraction. Signed: Laura Fisher, Executive Editor, RSC Advances. Date: 15th January 2021.
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1.  Semi-automated fact-checking of nucleotide sequence reagents in biomedical research publications: The Seek & Blastn tool.

Authors:  Cyril Labbé; Natalie Grima; Thierry Gautier; Bertrand Favier; Jennifer A Byrne
Journal:  PLoS One       Date:  2019-03-01       Impact factor: 3.752

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