| Literature DB >> 35421225 |
Rena R Wing1, Rebecca H Neiberg2, Judy L Bahnson2, Jeanne M Clark3, Mark A Espeland2, James O Hill4, Karen C Johnson5, William C Knowler6,7, KayLoni Olson1, Helmut Steinburg8, Xavier Pi-Sunyer9, Thomas A Wadden10, Holly Wyatt11, Jeanne M Clark3, Lee Swartz, Dawn Jiggetts, Jeanne Charleston, Lawrence Cheskin, Nisa M Maruthur, Scott J Pilla, Danielle Diggins, Mia Johnson, George A Bray, Frank L Greenway, Donna H Ryan, Catherine Champagne, Valerie Myers, Jeffrey Keller, Tiffany Stewart, Jennifer Arceneaux, Karen Boley, Greta Fry, Lisa Jones, Kim Landry, Melissa Lingle, Marisa Smith, Cora E Lewis, Sheikilya Thomas, Stephen Glasser, Gareth Dutton, Amy Dobelstein, Sara Hannum, Anne Hubbell, DeLavallade Lee, Phyllis Millhouse, L Christie Oden, Cathy Roche, Jackie Grant, Janet Turman, David M Nathan, Valerie Goldman, Linda Delahanty, Mary Larkin, Kristen Dalton, Roshni Singh, Melanie Ruazol, Medha N Munshi, Sharon D Jackson, Roeland J W Middelbeek, A Enrique Caballero, Anthony Rodriguez, George Blackburn, Christos Mantzoros, Ann McNamara, Holly Wyatt11, James O Hill4, Jeanne Anne Breen, Marsha Miller, Debbie Bochert, Suzette Bossart, Paulette Cohrs, Susan Green, April Hamilton, Eugene Leshchinskiy, Loretta Rome, John P Foreyt, Molly Gee, Henry Pownall, Ashok Balasubramanyam, Chu-Huang Chen, Peter Jones, Michele Burrington, Allyson Clark Gardner, Sharon Griggs, Michelle Hamilton, Veronica Holley, Sarah Lee, Sarah Lane Liscum, Susan Cantu-Lumbreras, Julieta Palencia, Jennifer Schmidt, Jayne Thomas, Carolyn White, Charlyne Wright, Monica Alvarez, Karen C Johnson5, Beate Griffin, Mace Coday, Donna Valenski, Lisa Jones, Karen Johnson, Karen C Johnson5, Helmut Steinburg8, Robert W Jeffery, Tricia Skarphol, John P Bantle, J Bruce Redmon, Kerrin Brelje, Carolyne Campbell, Mary Ann Forseth, Soni Uccellini, Mary Susan Voeller, Blandine Laferrère, Xavier Pi-Sunyer9, Jennifer Patricio, Jose Luchsinger, Priya Palta, Sarah Lyon, Kim Kelly, Thomas A Wadden10, Barbara J Maschak-Carey, Robert I Berkowitz, Ariana Chao, Renee Davenport, Katherine Gruber, Sharon Leonard, Olivia Walsh, John M Jakicic, Jacqueline Wesche-Thobaben, Lin Ewing, Andrea Hergenroeder, Mary Korytkowski, Susan Copelli, Rebecca Danchenko, Diane Ives, Juliet Mancino, Lisa Martich, Meghan McGuire, Tracey Y Murray, Linda Semler, Kathy Williams, Rena R Wing1, Caitlin Egan, Elissa Jelalian, Jeanne McCaffery, Kathryn Demos McDermott, Jessica Unick, Kirsten Annis, Jose DaCruz, Ariana Rafanelli, Helen P Hazuda, Juan Carlos Isaac, Prepedigna Hernandez, Steven E Kahn, Edward J Boyko, Elaine Tsai, Lorena Wright, Karen Atkinson, Ivy Morgan-Taggart, Jolanta Socha, Heidi Urquhart, William C Knowler6,7, Paula Bolin, Harelda Anderson, Sara Michaels, Ruby Johnson, Patricia Poorthunder, Janelia Smiley, Anne L Peters, Siran Ghazarian, Elizabeth Beale, Edgar Ramirez, Gabriela Rodriguez, Valerie Ruelas, Sara Serafin-Dokhan, Martha Walker, Marina Perez, Mark A Espeland2, Lynne E Wagenknecht, Judy L Bahnson2, David Reboussin, Mike E Miller, Peter Brubaker, Nicholas Pajewski, Michael Bancks, Jingzhong Ding, Gagan Deep, Kathleen Hayden, Stephen R Rapp, Felicia Simpson, Haiying Chen, Bonnie C Sachs, Denise Houston, Shyh-Huei Chen, Andrea Anderson, Jerry M Barnes, Mary Barr, Tara D Beckner, Delilah R Cook, Carrie C Williams, Joni Evans, Katie Garcia, Sarah A Gaussoin, Carol Kittel, Lea Harvin, Marjorie Howard, James Lovato, Rebecca H Neiberg2, June Pierce, Debbie Steinberg, Christopher Webb, Jennifer Walker, Michael P Walkup, Carolyn Watkins, Santica M Marcovina, Jessica Hurting, John J Albers, Vinod Gaur, Michael Nevitt, Ann Schwartz, John Shepherd, Michaela Rahorst, Lisa Palermo, Susan Ewing, Cynthia Hayashi, Jason Maeda.
Abstract
OBJECTIVE: Patients with type 2 diabetes are encouraged to lose weight, but excessive weight loss in older adults may be a marker of poor health and subsequent mortality. We examined weight change during the postintervention period of Look AHEAD, a randomized trial comparing intensive lifestyle intervention (ILI) with diabetes support and education (DSE) (control) in overweight/obese individuals with type 2 diabetes and sought to identify predictors of excessive postintervention weight loss and its association with mortality. RESEARCH DESIGN AND METHODS: These secondary analyses compared postintervention weight change (year 8 to final visit; median 16 years) in ILI and DSE in 3,999 Look AHEAD participants. Using empirically derived trajectory categories, we compared four subgroups: weight gainers (n = 307), weight stable (n = 1,561), steady losers (n = 1,731), and steep losers (n = 380), on postintervention mortality, demographic variables, and health status at randomization and year 8.Entities:
Year: 2022 PMID： 35421225 PMCID： PMC9277114 DOI： 10.2337/dc21-1990
Source DB: PubMed Journal: Diabetes Care ISSN： 0149-5992 Impact factor: 17.152