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Literature DB >> 35419621

The Enteroendocrine System in Obesity.

Emily L Miedzybrodzka¹, Frank Reimann¹, Fiona M Gribble².

Abstract

The enteroendocrine system coordinates the physiological response to food intake by regulating rates of digestion, nutrient absorption, insulin secretion, satiation and satiety. Gut hormones with important anorexigenic and/or insulinotropic roles include glucagon-like peptide 1 (GLP-1), peptide YY (PYY3-36), cholecystokinin (CCK) and glucose-dependent insulinotropic peptide (GIP). High BMI or obesogenic diets do not markedly disrupt this enteroendocrine system, which represents a critical target for inducing weight loss and treating co-morbidities in individuals with obesity.

Entities: Chemical

Keywords: CCK; Diabetes; Enteroendocrine; GIP; GLP-1; Gut hormone; Obesity; PYY

Mesh：

Substances：

Year: 2022 PMID： 35419621 DOI： 10.1007/164_2022_582

Source DB: PubMed Journal: Handb Exp Pharmacol ISSN： 0171-2004

136 in total

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Journal: Ann Oncol Date: 2001 Impact factor: 32.976

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Authors: Jasmine Bahrami; Christine Longuet; Laurie L Baggio; Karen Li; Daniel J Drucker
Journal: Gastroenterology Date: 2010-06-11 Impact factor: 22.682

3. Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake.

Authors: Caroline R Abbott; Caroline J Small; Adam R Kennedy; Nicola M Neary; Arshia Sajedi; Mohammad A Ghatei; Stephen R Bloom
Journal: Brain Res Date: 2005-05-10 Impact factor: 3.252

4. The inhibitory effects of peripheral administration of peptide YY(3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway.

Authors: Caroline R Abbott; Mariana Monteiro; Caroline J Small; Arshia Sajedi; Kirsty L Smith; James R C Parkinson; Mohammad A Ghatei; Stephen R Bloom
Journal: Brain Res Date: 2005-04-07 Impact factor: 3.252

5. Food intake in lean and obese mice after peripheral administration of glucagon-like peptide 2.

Authors: Sara Baldassano; Anna Lisa Bellanca; Rosa Serio; Flavia Mulè
Journal: J Endocrinol Date: 2012-03-28 Impact factor: 4.286

6. Glucagon-like peptide-1 release and satiety after a nutrient challenge in normal-weight and obese subjects.

Authors: Tanja C M Adam; Margriet S Westerterp-Plantenga
Journal: Br J Nutr Date: 2005-06 Impact factor: 3.718

7. Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans.

Authors: Meena Asmar; Lene Simonsen; Sten Madsbad; Bente Stallknecht; Jens Juul Holst; Jens Bülow
Journal: Diabetes Date: 2010-06-14 Impact factor: 9.461

8. Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.

Authors: Laurie L Baggio; Qingling Huang; Theodore J Brown; Daniel J Drucker
Journal: Gastroenterology Date: 2004-08 Impact factor: 22.682

9. Upregulated insulin secretion in insulin-resistant mice: evidence of increased islet GLP1 receptor levels and GPR119-activated GLP1 secretion.

Authors: L Ahlkvist; K Brown; B Ahrén
Journal: Endocr Connect Date: 2013-03-18 Impact factor: 3.335

10. Lipid-rich diet enhances L-cell density in obese subjects and in mice through improved L-cell differentiation.

Authors: Thomas Aranias; Alexandra Grosfeld; Christine Poitou; Amal Ait Omar; Maude Le Gall; Sylvie Miquel; Kévin Garbin; Agnès Ribeiro; Jean-Luc Bouillot; André Bado; Edith Brot-Laroche; Karine Clément; Armelle Leturque; Sandra Guilmeau; Patricia Serradas
Journal: J Nutr Sci Date: 2015-05-20

1 in total

1. Intestinal Enteroendocrine Cell Signaling: Retinol-binding Protein 2 and Retinoid Actions.

Authors: Rossana M Calderon; Christopher A Smith; Emily L Miedzybrodzka; Josie A Silvaroli; Marcin Golczak; Fiona M Gribble; Frank Reimann; William S Blaner
Journal: Endocrinology Date: 2022-07-01 Impact factor: 5.051

1 in total