Literature DB >> 35418629

What's next for AlphaFold and the AI protein-folding revolution.

Ewen Callaway.   

Abstract

Entities:  

Keywords:  Biological techniques; Computational biology and bioinformatics; Drug discovery; Structural biology

Mesh：

Year:  2022        PMID： 35418629     DOI： 10.1038/d41586-022-00997-5

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


× No keyword cloud information.
  4 in total

1.  De novo protein design by deep network hallucination.

Authors:  Ivan Anishchenko; Samuel J Pellock; Tamuka M Chidyausiku; Theresa A Ramelot; Sergey Ovchinnikov; Jingzhou Hao; Khushboo Bafna; Christoffer Norn; Alex Kang; Asim K Bera; Frank DiMaio; Lauren Carter; Cameron M Chow; Gaetano T Montelione; David Baker
Journal:  Nature       Date:  2021-12-01       Impact factor: 69.504

2.  Computed structures of core eukaryotic protein complexes.

Authors:  Ian R Humphreys; Jimin Pei; Minkyung Baek; Aditya Krishnakumar; Qian Cong; David Baker; Ivan Anishchenko; Sergey Ovchinnikov; Jing Zhang; Travis J Ness; Sudeep Banjade; Saket R Bagde; Viktoriya G Stancheva; Xiao-Han Li; Kaixian Liu; Zhi Zheng; Daniel J Barrero; Upasana Roy; Jochen Kuper; Israel S Fernández; Barnabas Szakal; Dana Branzei; Josep Rizo; Caroline Kisker; Eric C Greene; Sue Biggins; Scott Keeney; Elizabeth A Miller; J Christopher Fromme; Tamara L Hendrickson
Journal:  Science       Date:  2021-12-10       Impact factor: 63.714

3.  Accurate prediction of protein structures and interactions using a three-track neural network.

Authors:  Minkyung Baek; Frank DiMaio; Ivan Anishchenko; Justas Dauparas; Sergey Ovchinnikov; Gyu Rie Lee; Jue Wang; Qian Cong; Lisa N Kinch; R Dustin Schaeffer; Claudia Millán; Hahnbeom Park; Carson Adams; Caleb R Glassman; Andy DeGiovanni; Jose H Pereira; Andria V Rodrigues; Alberdina A van Dijk; Ana C Ebrecht; Diederik J Opperman; Theo Sagmeister; Christoph Buhlheller; Tea Pavkov-Keller; Manoj K Rathinaswamy; Udit Dalwadi; Calvin K Yip; John E Burke; K Christopher Garcia; Nick V Grishin; Paul D Adams; Randy J Read; David Baker
Journal:  Science       Date:  2021-07-15       Impact factor: 47.728

4.  Highly accurate protein structure prediction with AlphaFold.

Authors:  John Jumper; Richard Evans; Alexander Pritzel; Tim Green; Michael Figurnov; Olaf Ronneberger; Kathryn Tunyasuvunakool; Russ Bates; Augustin Žídek; Anna Potapenko; Alex Bridgland; Clemens Meyer; Simon A A Kohl; Andrew J Ballard; Andrew Cowie; Bernardino Romera-Paredes; Stanislav Nikolov; Rishub Jain; Demis Hassabis; Jonas Adler; Trevor Back; Stig Petersen; David Reiman; Ellen Clancy; Michal Zielinski; Martin Steinegger; Michalina Pacholska; Tamas Berghammer; Sebastian Bodenstein; David Silver; Oriol Vinyals; Andrew W Senior; Koray Kavukcuoglu; Pushmeet Kohli
Journal:  Nature       Date:  2021-07-15       Impact factor: 49.962
  4 in total
  7 in total

Review 1.  From Traditional Ethnopharmacology to Modern Natural Drug Discovery: A Methodology Discussion and Specific Examples.

Authors:  Stergios Pirintsos; Athanasios Panagiotopoulos; Michalis Bariotakis; Vangelis Daskalakis; Christos Lionis; George Sourvinos; Ioannis Karakasiliotis; Marilena Kampa; Elias Castanas
Journal:  Molecules       Date:  2022-06-24       Impact factor: 4.927

2.  Computational design and characterization of a multiepitope vaccine against carbapenemase-producing Klebsiella pneumoniae strains, derived from antigens identified through reverse vaccinology.

Authors:  Nicola Cuscino; Ayesha Fatima; Vincenzo Di Pilato; Matteo Bulati; Caterina Alfano; Elisa Monaca; Giuseppina Di Mento; Daniele Di Carlo; Francesca Cardinale; Francesco Monaco; Gian Maria Rossolini; Asif M Khan; Pier Giulio Conaldi; Bruno Douradinha
Journal:  Comput Struct Biotechnol J       Date:  2022-08-17       Impact factor: 6.155

Review 3.  Opportunities and Challenges for In Silico Drug Discovery at Delta Opioid Receptors.

Authors:  Yazan J Meqbil; Richard M van Rijn
Journal:  Pharmaceuticals (Basel)       Date:  2022-07-15

4.  Diving into the Deep End: Machine Learning for the Chemist.

Authors:  Silvia Imberti
Journal:  ACS Omega       Date:  2022-07-20

5.  Importins involved in the nuclear transportation of steroid hormone receptors: In silico and in vitro data.

Authors:  Konstantina Kalyvianaki; Athanasios A Panagiotopoulos; Maria Patentalaki; Elias Castanas; Marilena Kampa
Journal:  Front Endocrinol (Lausanne)       Date:  2022-09-06       Impact factor: 6.055

6.  Effect of Delta and Omicron Mutations on the RBD-SD1 Domain of the Spike Protein in SARS-CoV-2 and the Omicron Mutations on RBD-ACE2 Interface Complex.

Authors:  Wai-Yim Ching; Puja Adhikari; Bahaa Jawad; Rudolf Podgornik
Journal:  Int J Mol Sci       Date:  2022-09-03       Impact factor: 6.208

Review 7.  Computational approaches for predicting variant impact: An overview from resources, principles to applications.

Authors:  Ye Liu; William S B Yeung; Philip C N Chiu; Dandan Cao
Journal:  Front Genet       Date:  2022-09-29       Impact factor: 4.772
  7 in total

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