Literature DB >> 35416798

Racial Disparities in Associations of Alcohol Consumption With Liver Disease Mortality in a Predominantly Low-Income Population: A Report From the Southern Community Cohort Study.

Lei Fan1, Xiangzhu Zhu1, Alexandra Shingina2, Edmond K Kabagambe3, Martha J Shrubsole1, Qi Dai1.   

Abstract

Consistent with previous cross-sectional studies, in the Southern Community Cohort Study, the largest cohort for Black Americans conducted in a predominantly low-income population with 81,694 participants, we found that moderate alcohol drinking was associated with a significantly increased risk of mortality due to liver disease in Black Americans (hazard ratio = 2.06; 95% confidence interval: 1.08-3.94) but not in White Americans (hazard ratio = 0.87; 95% confidence interval: 0.52-1.44). We found that heavy drinking was significantly associated with an increased risk of mortality due to liver disease in both Black and White Americans. Future studies are warranted to understand the mechanism involving such racial disparity.
Copyright © 2022 by The American College of Gastroenterology.

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Year:  2022        PMID: 35416798      PMCID: PMC9437117          DOI: 10.14309/ajg.0000000000001768

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   12.045


  34 in total

1.  Racial and ethnic differences in alcohol-associated aspartate aminotransferase and gamma-glutamyltransferase elevation.

Authors:  Scott H Stewart
Journal:  Arch Intern Med       Date:  2002-10-28

2.  The Southern Community Cohort Study: investigating health disparities.

Authors:  Lisa B Signorello; Margaret K Hargreaves; William J Blot
Journal:  J Health Care Poor Underserved       Date:  2010-02

3.  Genetic variation in alcohol metabolizing enzymes: implications in alcohol use and abuse.

Authors:  D P Agarwal; H W Goedde
Journal:  Prog Clin Biol Res       Date:  1987

4.  Dietary Guidelines for Americans, 2020-2025.

Authors:  Jennan A Phillips
Journal:  Workplace Health Saf       Date:  2021-08       Impact factor: 1.413

5.  Effect of Alcohol Consumption on Survival in Nonalcoholic Fatty Liver Disease: A National Prospective Cohort Study.

Authors:  Kaveh Hajifathalian; Babak Torabi Sagvand; Arthur J McCullough
Journal:  Hepatology       Date:  2018-10-02       Impact factor: 17.425

6.  A multi-stage approach to maximizing geocoding success in a large population-based cohort study through automated and interactive processes.

Authors:  Jennifer S Sonderman; Michael T Mumma; Sarah S Cohen; Elizabeth L Cope; William J Blot; Lisa B Signorello
Journal:  Geospat Health       Date:  2012-05       Impact factor: 1.212

7.  Ethnic differences in presentation and severity of alcoholic liver disease.

Authors:  Robert Levy; Andreea M Catana; Blythe Durbin-Johnson; Charles H Halsted; Valentina Medici
Journal:  Alcohol Clin Exp Res       Date:  2015-02-20       Impact factor: 3.455

8.  Alcohol consumption is associated with progression of hepatic fibrosis in non-alcoholic fatty liver disease.

Authors:  Mattias Ekstedt; Lennart E Franzén; Marika Holmqvist; Preben Bendtsen; Ulrik L Mathiesen; Göran Bodemar; Stergios Kechagias
Journal:  Scand J Gastroenterol       Date:  2009       Impact factor: 2.423

9.  Mortality due to cirrhosis and liver cancer in the United States, 1999-2016: observational study.

Authors:  Elliot B Tapper; Neehar D Parikh
Journal:  BMJ       Date:  2018-07-18

Review 10.  Disparities in Cardiovascular Disease and Type 2 Diabetes Risk Factors in Blacks and Whites: Dissecting Racial Paradox of Metabolic Syndrome.

Authors:  Kwame Osei; Trudy Gaillard
Journal:  Front Endocrinol (Lausanne)       Date:  2017-08-31       Impact factor: 5.555

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