| Literature DB >> 3541555 |
Z Farfel, M Shechter, Z Vered, S Rath, D Goor, J Gafni.
Abstract
2DE permits detection of thromboemboli transiently entrapped in the right heart chambers while en route to the pulmonary arteries. Review of the 49 cases recorded to date reveals that the supple elongated clot produces a 2DE picture--a mass of changing configuration and striking mobility--that is highly characteristic. Since emboli that become entrapped are large, when managed by medical measures alone they have an attendant mortality rate of 50%, usually soon after 2DE diagnosis, upon completion of pulmonary embolization. Death occurred in 8 of 16 patients treated with anticoagulants, thrombolytic agents, or antiaggregants and in 6 of 13 who received supportive measures only. Of 20 patients referred for surgery (cardiotomy and, in 17, pulmonary embolectomy), only three died, two of them failures of preceding anticoagulant treatment. These data indicate that thromboemboli entrapped in the right heart chambers are best handled as a surgical emergency.Entities:
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Year: 1987 PMID: 3541555 DOI: 10.1016/0002-8703(87)90026-3
Source DB: PubMed Journal: Am Heart J ISSN: 0002-8703 Impact factor: 4.749