| Literature DB >> 35411728 |
Jieun Kim1, Juhui Han1, Byung Chul Chun1,2.
Abstract
BACKGROUND: The effect of coronavirus disease 2019 (COVID-19) pandemic on public mental health has been increasing. Additionally, the underlying psychological stressors remain unexplored, and few studies have been conducted nationally on the social distancing measures. Therefore, the present study aimed to identify the psychological impacts of the implementation of social distancing measures by analyzing the Internet search trends of major depressive disorder (MDD) symptoms.Entities:
Keywords: COVID-19; Interrupted Time-Series Analysis; Major Depressive Disorder; Physical Distancing
Mesh:
Year: 2022 PMID: 35411728 PMCID: PMC9001188 DOI: 10.3346/jkms.2022.37.e108
Source DB: PubMed Journal: J Korean Med Sci ISSN: 1011-8934 Impact factor: 2.153
Descriptive statistics for the search terms’ weekly relative search volumes (RSVs) from January 1, 2016–December 31, 2020 (Number of weekly RSVs = 262)
| Terms | Mean | Standard deviation | Median |
|---|---|---|---|
| Depressed mood | 34.45 | 14.00 | 32.79 |
| Hopelessness | 12.61 | 7.78 | 11.66 |
| Sexual desire | 43.94 | 10.51 | 40.15 |
| Decreased weight | 44.25 | 9.33 | 42.68 |
| Increased weight | 44.48 | 11.01 | 42.86 |
| Decreased appetite | 43.63 | 8.42 | 42.67 |
| Increased appetite | 31.39 | 18.35 | 22.44 |
| Insomnia | 14.22 | 6.07 | 12.08 |
| Hypersomnia | 25.60 | 6.45 | 24.88 |
| Restlessness | 24.46 | 3.77 | 23.64 |
| Feeling lethargic | 41.90 | 10.92 | 41.50 |
| Feeling fatigue | 36.43 | 9.18 | 34.78 |
| Feeling guilty | 51.10 | 7.11 | 49.69 |
| Impaired concentration | 25.58 | 9.30 | 24.22 |
| Indecisiveness | 35.54 | 5.54 | 34.34 |
| Wanting to die | 52.72 | 7.17 | 51.75 |
Descriptive statistics for the search terms’ daily relative search volumes (RSVs) from January 1, 2016–December 31, 2020 (Number of daily RSVs = 366)
| Terms | Mean | Standard deviation | Median |
|---|---|---|---|
| Depressed mood | 54.03 | 13.72 | 53.63 |
| Hopelessness | 28.90 | 20.46 | 25.71 |
| Sexual desire | 39.98 | 6.38 | 39.13 |
| Decreased weight | 47.28 | 11.48 | 45.83 |
| Increased weight | 51.55 | 16.21 | 50.77 |
| Decreased appetite | 51.13 | 13.67 | 50.00 |
| Increased appetite | 44.39 | 15.91 | 42.50 |
| Insomnia | 18.23 | 10.10 | 15.36 |
| Hypersomnia | 37.48 | 13.04 | 36.36 |
| Restlessness | 39.41 | 8.88 | 38.83 |
| Feeling lethargic | 51.01 | 17.37 | 50.79 |
| Feeling fatigue | 52.35 | 15.70 | 50.99 |
| Feeling guilty | 61.43 | 10.41 | 60.99 |
| Impaired concentration | 35.66 | 15.89 | 34.78 |
Estimated coefficients from interrupted time-series analysis using an autoregressive integrated moving average model
| Symptoms | Category | β1 (time effect) | β2 (level change) | β3 (trend change) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Estimate | SE | Estimate | SE | Estimate | SE | |||||
| Depressed mood | All | 0.131 | 0.010 | < 0.001 | 5.699 | 3.523 | 0.107 | 0.131 | 0.135 | 0.332 |
| Male | 0.066 | 0.004 | < 0.001 | 3.971 | 1.850 | 0.033 | 0.041 | 0.070 | 0.557 | |
| Female | 0.147 | 0.011 | < 0.001 | 4.472 | 3.750 | 0.235 | 0.139 | 0.144 | 0.336 | |
| Hopelessness | All | −0.065 | 0.008 | < 0.001 | 10.413 | 3.486 | 0.003 | 0.086 | 0.137 | 0.531 |
| Male | −0.069 | 0.008 | < 0.001 | 13.635 | 4.043 | < 0.001 | 0.091 | 0.157 | 0.564 | |
| Female | −0.078 | 0.010 | < 0.001 | 18.650 | 4.842 | < 0.001 | 0.083 | 0.191 | 0.665 | |
| Sexual desire | All | −0.146 | 0.030 | < 0.001 | 9.769 | 2.503 | < 0.001 | −0.005 | 0.150 | 0.975 |
| Male | −0.117 | 0.017 | < 0.001 | 9.976 | 2.329 | < 0.001 | −0.004 | 0.117 | 0.976 | |
| Female | −0.116 | 0.026 | < 0.001 | 8.125 | 2.741 | 0.003 | 0.049 | 0.143 | 0.733 | |
| Decreased weight | All | 0.022 | 0.034 | 0.520 | −7.020 | 4.739 | 0.140 | 0.067 | 0.279 | 0.810 |
| Male | 0.046 | 0.019 | 0.016 | 2.714 | 4.854 | 0.577 | −0.173 | 0.198 | 0.382 | |
| Female | 0.030 | 0.030 | 0.330 | 1.231 | 5.226 | 0.814 | −0.045 | 0.245 | 0.854 | |
| Increased weight | All | 0.022 | 0.034 | 0.520 | −7.020 | 4.739 | 0.140 | 0.067 | 0.279 | 0.810 |
| Male | −0.101 | 0.018 | < 0.001 | −2.816 | 4.140 | 0.497 | 0.109 | 0.162 | 0.502 | |
| Female | −0.041 | 0.018 | 0.023 | 5.001 | 3.844 | 0.195 | 0.010 | 0.164 | 0.953 | |
| Decreased appetite | All | −0.009 | 0.028 | 0.745 | 7.804 | 4.447 | 0.081 | −0.080 | 0.210 | 0.702 |
| Male | 0.016 | 0.019 | 0.377 | 10.349 | 4.263 | 0.016 | −0.175 | 0.162 | 0.281 | |
| Female | 0.014 | 0.021 | 0.524 | 10.779 | 3.835 | 0.005 | −0.147 | 0.160 | 0.360 | |
| Increased appetite | All | −0.020 | 0.089 | 0.825 | 5.646 | 5.610 | 0.315 | −0.481 | 0.549 | 0.381 |
| Male | 0.001 | 0.061 | 0.989 | 6.176 | 5.669 | 0.277 | −0.442 | 0.407 | 0.278 | |
| Female | −0.010 | 0.084 | 0.906 | 7.794 | 5.479 | 0.156 | −0.479 | 0.493 | 0.333 | |
| Insomnia | All | −0.057 | 0.027 | 0.037 | 7.686 | 2.467 | 0.002 | 0.056 | 0.175 | 0.750 |
| Male | 0.008 | 0.003 | 0.004 | 12.178 | 1.075 | < 0.001 | −0.280 | 0.040 | < 0.001 | |
| Female | 0.023 | 0.004 | < 0.0001 | 11.652 | 1.587 | < 0.001 | −0.207 | 0.060 | < 0.001 | |
| Hypersomnia | All | −0.053 | 0.013 | < 0.001 | 12.138 | 3.237 | < 0.001 | −0.059 | 0.129 | 0.651 |
| Male | −0.030 | 0.007 | < 0.001 | 7.377 | 2.189 | < 0.001 | −0.098 | 0.079 | 0.219 | |
| Female | −0.028 | 0.014 | 0.052 | 9.646 | 3.359 | 0.005 | 0.053 | 0.146 | 0.720 | |
| Restlessness | All | 0.000 | 0.001 | 0.697 | 8.399 | 0.705 | < 0.001 | −0.111 | 0.029 | 0.000 |
| Male | 0.014 | 0.001 | < 0.001 | 5.710 | 0.718 | < 0.001 | −0.065 | 0.028 | 0.020 | |
| Female | 0.022 | 0.001 | < 0.001 | 10.097 | 0.634 | < 0.001 | −0.170 | 0.026 | < 0.001 | |
| Feeling lethargic | All | −0.034 | 0.022 | 0.110 | 20.837 | 4.661 | < 0.001 | −0.110 | 0.180 | 0.543 |
| Male | −0.002 | 0.016 | 0.920 | 9.693 | 3.540 | 0.007 | −0.041 | 0.134 | 0.758 | |
| Female | −0.012 | 0.017 | 0.465 | 15.693 | 4.016 | < 0.001 | −0.141 | 0.157 | 0.372 | |
| Feeling fatigue | All | 0.029 | 0.020 | 0.163 | 6.064 | 4.917 | 0.219 | −0.112 | 0.205 | 0.588 |
| Male | 0.026 | 0.004 | < 0.001 | 17.180 | 2.107 | < 0.001 | −0.159 | 0.085 | 0.061 | |
| Female | 0.034 | 0.010 | 0.001 | 10.496 | 3.643 | 0.004 | 0.033 | 0.139 | 0.812 | |
| Feeling guilty | All | 0.027 | 0.009 | 0.003 | 0.080 | 2.724 | 0.977 | 0.425 | 0.112 | < 0.001 |
| Male | 0.036 | 0.006 | < 0.001 | 1.115 | 2.230 | 0.618 | 0.146 | 0.085 | 0.089 | |
| Female | 0.056 | 0.009 | < 0.001 | 3.046 | 2.763 | 0.272 | 0.365 | 0.111 | < 0.001 | |
| Impaired concentration | All | 0.040 | 0.021 | 0.053 | −4.036 | 4.401 | 0.360 | 0.103 | 0.172 | 0.549 |
| Male | 0.042 | 0.004 | < 0.001 | −16.888 | 2.204 | < 0.001 | 0.539 | 0.090 | < 0.001 | |
| Female | 0.049 | 0.023 | 0.033 | 2.143 | 3.858 | 0.580 | −0.089 | 0.186 | 0.634 | |
| Indecisiveness | All | 0.003 | 0.012 | 0.825 | 3.918 | 2.336 | 0.095 | 0.094 | 0.115 | 0.414 |
| Male | 0.013 | 0.007 | 0.061 | 3.253 | 2.601 | 0.212 | 0.118 | 0.104 | 0.261 | |
| Female | 0.023 | 0.012 | 0.055 | 3.515 | 2.056 | 0.089 | 0.027 | 0.108 | 0.803 | |
| Wanting to die | All | −0.074 | 0.014 | < 0.001 | −2.241 | 2.738 | 0.414 | 0.399 | 0.125 | < 0.001 |
| Male | −0.065 | 0.013 | < 0.001 | −3.997 | 2.936 | 0.175 | 0.255 | 0.130 | 0.051 | |
| Female | −0.045 | 0.013 | 0.001 | −4.164 | 2.971 | 0.163 | 0.511 | 0.125 | < 0.001 | |
SE = standard error.
Correlation coefficients between internet relative search volumes of each depressive symptom and number of total coronavirus disease 2019 confirmed cases from January 1–December 31, 2020
| Symptoms | Coefficient | |
|---|---|---|
| Depressed mood | 0.444 | < 0.001 |
| Hopelessness | 0.290 | < 0.001 |
| Sexual desire | −0.337 | < 0.001 |
| Decreased weight | −0.184 | < 0.001 |
| Increased weight | −0.394 | < 0.001 |
| Decreased appetite | −0.160 | < 0.001 |
| Increased appetite | −0.333 | < 0.001 |
| Insomnia | −0.304 | < 0.001 |
| Hypersomnia | −0.092 | 0.078 |
| Restlessness | −0.052 | 0.326 |
| Feeling lethargic | 0.008 | 0.881 |
| Feeling fatigue | 0.033 | 0.523 |
| Feeling guilty | 0.160 | 0.001 |
| Impaired concentration | 0.440 | < 0.001 |
| Indecisiveness | 0.223 | < 0.001 |
| Wanting to die | 0.524 | < 0.001 |
Difference of internet relative search volumes of each symptom by the level of social distancing measures
| Symptoms | Below level 2 distancing | Level 2 or higher distancing | |||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Depressed mood | 52.391 | 13.651 | 59.203 | 12.677 | < 0.001 |
| Hopelessness | 41.426 | 14.848 | 38.636 | 11.151 | 0.138 |
| Sexual desire | 29.291 | 21.926 | 27.662 | 14.953 | 0.925 |
| Decreased weight | 40.474 | 6.803 | 38.400 | 4.500 | 0.006 |
| Increased weight | 48.076 | 11.259 | 44.763 | 11.863 | 0.005 |
| Decreased appetite | 54.770 | 16.264 | 41.381 | 11.038 | < 0.001 |
| Increased appetite | 51.762 | 13.827 | 49.140 | 13.019 | 0.246 |
| Insomnia | 44.065 | 16.462 | 45.398 | 14.050 | 0.284 |
| Hypersomnia | 18.960 | 11.239 | 15.923 | 4.337 | 0.193 |
| Restlessness | 38.893 | 13.463 | 33.006 | 10.461 | < 0.001 |
| Feeling lethargic | 39.299 | 9.209 | 39.759 | 7.800 | 0.301 |
| Feeling fatigue | 51.239 | 17.407 | 50.289 | 17.324 | 0.502 |
| Feeling guilty | 51.572 | 14.981 | 54.801 | 17.645 | 0.226 |
| Impaired concentration | 61.025 | 11.227 | 62.705 | 7.167 | 0.038 |
| Indecisiveness | 32.885 | 14.589 | 44.433 | 16.709 | < 0.001 |
| Wanting to die | 41.902 | 8.769 | 42.336 | 4.903 | 0.268 |
SD = standard deviation.