Evangelia Koutelou1,2, Sharon Y R Dent3,4. 1. Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA. ekoutelou@mdanderson.org. 2. Center for Cancer Epigenetics, University of Texas MD Anderson Cancer Center, Houston, TX, USA. ekoutelou@mdanderson.org. 3. Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Houston, TX, USA. sroth@mdanderson.org. 4. Center for Cancer Epigenetics, University of Texas MD Anderson Cancer Center, Houston, TX, USA. sroth@mdanderson.org.