Literature DB >> 35410675

The Burden of Osteoarthritis in Older Adults.

Gillian A Hawker1, Lauren K King2.   

Abstract

Osteoarthritis (OA) is the most common form of arthritis and a leading cause of disability among older people. One in 3 people over age 65, and disproportionately more women than men, are living with OA. The prevalence of OA is rising related to an increasing prevalence of OA risk factors, including aging and obesity. In older adults, OA frequently exists alongside other common chronic conditions and may increase the risk for worse outcomes from these conditions. Given the growing burden and impact of OA, enhanced effort is required to deliver effective and safe treatments to those living with the disease.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Economic burden; Incidence; Osteoarthritis; Prevalence; Risk factors

Mesh:

Year:  2022        PMID: 35410675     DOI: 10.1016/j.cger.2021.11.005

Source DB:  PubMed          Journal:  Clin Geriatr Med        ISSN: 0749-0690            Impact factor:   3.076


  2 in total

1.  Oral Administration of Clostridium butyricum GKB7 Ameliorates Signs of Osteoarthritis in Rats.

Authors:  Sunny Li-Yun Chang; Yen-You Lin; Shan-Chi Liu; You-Shan Tsai; Shih-Wei Lin; Yen-Lien Chen; Chin-Chu Chen; Chih-Yuan Ko; Hsien-Te Chen; Wei-Cheng Chen; Chih-Hsin Tang
Journal:  Cells       Date:  2022-07-11       Impact factor: 7.666

2.  Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.

Authors:  Zengxin Jiang; Guobin Qi; Wei Lu; Hao Wang; Defang Li; Weibin Chen; Lei Ding; Xiuying Yang; Hengfeng Yuan; Qingmin Zeng
Journal:  Front Pharmacol       Date:  2022-09-27       Impact factor: 5.988

  2 in total

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