Literature DB >> 35402138

Cushing syndrome secondary to a mediastinal carcinoid tumor: a case report.

Reza Ershadi1, Matin Vahedi1, Behnaz Jahanbin2, Javad Sarbazzadeh1, Shahab Rafieian1.   

Abstract

Neuroendocrine tumors (NET) are a rare and diverse set of malignancies that can develop anywhere within the body. ACTH-producing mediastinal NETs often originate from the thymus in the anterior mediastinum and are very rare. Primary diagnostic modalities for NETs include CT scan, MRI, scintigraphy, and Ga-DOTA PET scan. Here we report a case of a young male without any past medical history presenting with hypercortisolism secondary to a middle mediastinal typical carcinoid tumor. The patient underwent a successful resection which reduced serum ACTH levels. To the best of our knowledge, this is the first case of Cushing syndrome caused by a middle mediastinal NET.
© The Author(s) under exclusive licence to The Japan Society of Clinical Oncology 2022.

Entities:  

Keywords:  ACTH syndrome; Carcinoid tumor; Cushing’s syndrome; Ectopic; Mediastinal neoplasms; Neuroendocrine tumor

Year:  2022        PMID: 35402138      PMCID: PMC8938558          DOI: 10.1007/s13691-022-00542-1

Source DB:  PubMed          Journal:  Int Cancer Conf J        ISSN: 2192-3183


  10 in total

1.  The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline.

Authors:  Lynnette K Nieman; Beverly M K Biller; James W Findling; John Newell-Price; Martin O Savage; Paul M Stewart; Victor M Montori
Journal:  J Clin Endocrinol Metab       Date:  2008-03-11       Impact factor: 5.958

Review 2.  Pancreatic neuroendocrine tumors: a review.

Authors:  Kate Young; Ridhima Iyer; Daniel Morganstein; Ian Chau; David Cunningham; Naureen Starling
Journal:  Future Oncol       Date:  2015       Impact factor: 3.404

3.  The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics.

Authors:  Elena Valassi; Alicia Santos; Maria Yaneva; Miklós Tóth; Christian J Strasburger; Philippe Chanson; John A H Wass; Olivier Chabre; Marija Pfeifer; Richard A Feelders; Stylianos Tsagarakis; Peter J Trainer; Holger Franz; Kathrin Zopf; Sabina Zacharieva; Steven W J Lamberts; Antoine Tabarin; Susan M Webb
Journal:  Eur J Endocrinol       Date:  2011-06-29       Impact factor: 6.664

Review 4.  Advanced typical and atypical carcinoid tumours of the lung: management recommendations.

Authors:  B Melosky
Journal:  Curr Oncol       Date:  2018-06-13       Impact factor: 3.677

5.  Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline.

Authors:  Lynnette K Nieman; Beverly M K Biller; James W Findling; M Hassan Murad; John Newell-Price; Martin O Savage; Antoine Tabarin
Journal:  J Clin Endocrinol Metab       Date:  2015-07-29       Impact factor: 5.958

6.  Evaluation and Treatment of Patients With Hypercortisolism: A Review.

Authors:  Barbra S Miller; Richard J Auchus
Journal:  JAMA Surg       Date:  2020-12-01       Impact factor: 14.766

Review 7.  Cardiovascular risk and mortality in patients with active and treated hypercortisolism.

Authors:  Dingfeng Li; Omar M El Kawkgi; Andres F Henriquez; Irina Bancos
Journal:  Gland Surg       Date:  2020-02

8.  Invasive atypical thymic carcinoid: three case reports and literature review.

Authors:  Shan Zhu; Zhong-Tang Wang; Wen-Zhi Liu; Shi-Xiang Zong; Bao-Sheng Li
Journal:  Onco Targets Ther       Date:  2016-10-11       Impact factor: 4.147

Review 9.  Nothing But NET: A Review of Neuroendocrine Tumors and Carcinomas.

Authors:  Bryan Oronsky; Patrick C Ma; Daniel Morgensztern; Corey A Carter
Journal:  Neoplasia       Date:  2017-11-05       Impact factor: 5.715

10.  Effect of hypercortisolism on bone mineral density and bone metabolism: A potential protective effect of adrenocorticotropic hormone in patients with Cushing's disease.

Authors:  Weihong Guo; Fengao Li; Chonggui Zhu; Baoping Wang; Kunling Wang; Chenlin Dai; Hongwei Jia; Hongyan Wei; Qing He; Jin Cui; Menghua Yuan; Shaofang Tang; Wei Liu; Tiehong Zhu; Zhihong Gao; Fangqiu Zheng; Zhongshu Ma; Huiqi Qu; Mei Zhu
Journal:  J Int Med Res       Date:  2017-08-29       Impact factor: 1.671

  10 in total

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