Literature DB >> 35399174

A Brief Overview of Oncogenes and Signal Transduction Pathways in Gynecological Cancer.

Emmanuel N Kontomanolis1, Antonios Koutras2, Zacharias Fasoulakis2, Athanasios Syllaios3, Michail Diakosavvas2, Kyveli Angelou2, Panagiotis Symeonidis4, Athina A Samara5, Vasilios Pergialiotis2, Nikolaos Garmpis3, Dimitrios Schizas3, Athanasios Pagkalos6, Athanasios Chionis7, Georgios Daskalakis2, Thomas Ntounis2.   

Abstract

Gynecological cancer is the cancer that originates in the female reproductive system. According to the anatomical location of the cancer, it is distinguished into cervical, uterine, vaginal, ovarian, and vulvar cancer. Oncogenes and tumor catalytic genes play a key role in the genesis and development of gynecological cancer. This article presents the signaling pathways and expression of oncogenes that take place in the carcinogenesis of the female reproductive system. Copyright 2022, International Institute of Anticancer Research.

Entities:  

Keywords:  Oncogenes; gynecological cancer; molecular biology; review; signal transduction

Year:  2022        PMID: 35399174      PMCID: PMC8962808          DOI: 10.21873/cdp.10087

Source DB:  PubMed          Journal:  Cancer Diagn Progn        ISSN: 2732-7787


  69 in total

1.  Factors associated with late diagnosis of cervical cancer in Nepal.

Authors:  Deepak Gyenwali; Jitendra Pariyar; Sharad Raj Onta
Journal:  Asian Pac J Cancer Prev       Date:  2013

Review 2.  Diagnosis and management of cervical cancer.

Authors:  Patrick Petignat; Michel Roy
Journal:  BMJ       Date:  2007-10-13

3.  PIK3CA as an oncogene in cervical cancer.

Authors:  Y Y Ma; S J Wei; Y C Lin; J C Lung; T C Chang; J Whang-Peng; J M Liu; D M Yang; W K Yang; C Y Shen
Journal:  Oncogene       Date:  2000-05-25       Impact factor: 9.867

4.  Pattern of presentation of cervical carcinoma at Nuclear Institute of Medicine and Radiotherapy, Pakistan.

Authors:  Nousheen Aziz; Sajida Yousfani
Journal:  Pak J Med Sci       Date:  2013-05       Impact factor: 1.088

Review 5.  Primary vaginal cancer.

Authors:  A Goodman
Journal:  Surg Oncol Clin N Am       Date:  1998-04       Impact factor: 3.495

6.  Identification of Pbx1, a potential oncogene, as a Notch3 target gene in ovarian cancer.

Authors:  Joon T Park; Ie-Ming Shih; Tian-Li Wang
Journal:  Cancer Res       Date:  2008-11-01       Impact factor: 12.701

7.  Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas.

Authors:  A Bellacosa; D de Feo; A K Godwin; D W Bell; J Q Cheng; D A Altomare; M Wan; L Dubeau; G Scambia; V Masciullo; G Ferrandina; P Benedetti Panici; S Mancuso; G Neri; J R Testa
Journal:  Int J Cancer       Date:  1995-08-22       Impact factor: 7.396

8.  PRMT6 promotes endometrial cancer via AKT/mTOR signaling and indicates poor prognosis.

Authors:  Nan Jiang; Qiu-Li Li; Wenwei Pan; Jinhui Li; Mei-Fang Zhang; Tiefeng Cao; Shu-Guang Su; Huimin Shen
Journal:  Int J Biochem Cell Biol       Date:  2019-12-26       Impact factor: 5.085

9.  Retrospective review of symptoms and palliative care interventions in women with advanced cervical cancer.

Authors:  Yu Jung Kim; Mark F Munsell; Ji Chan Park; Larissa A Meyer; Charlotte C Sun; Alaina J Brown; Diane C Bodurka; Janet L Williams; Dana M Chase; Eduardo Bruera; Lois M Ramondetta
Journal:  Gynecol Oncol       Date:  2015-09-30       Impact factor: 5.482

10.  An overview of prevention and early detection of cervical cancers.

Authors:  Gauravi A Mishra; Sharmila A Pimple; Surendra S Shastri
Journal:  Indian J Med Paediatr Oncol       Date:  2011-07
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