Miloslav Marel1, Zdenka Chladkova1, Luis Fernando Casas Mendez1, Ondrej Venclicek2, Jana Skrickova2, Ondej Fischer3, Andrea Mullerova3, Libor Havel4, Zuzana Gyorfy4, Michal Hrnciarik5, Michal Jirousek5, Jana Krejci6, Daniel Krejci6, Marcela Buresova7, Jana Alahakoon8, Michal Svoboda9, Martin Svaton7. 1. Department of Pulmonology, 2nd Faculty of Medicine, Charles University, University Hospital Motol, Prague, Czech Republic. 2. Department of Respiratory Diseases, Faculty of Medicine, Masaryk University, University Hospital, Brno, Czech Republic. 3. Department of Respiratory Medicine, University Hospital, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic. 4. Department of Respiratory Medicine, Thomayer Hospital, 1st Faculty of Medicine, Charles University, Prague, Czech Republic. 5. Pulmonary Department, University Hospital, Charles University, Faculty of Medicine, Hradec Kralove, Czech Republic. 6. Department of Pneumology, Bulovka University Hospital, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic. 7. Department of Pneumology and Phthiseology, University Hospital, Faculty of Medicine in Pilsen, Charles University, Pilsen, Czech Republic. 8. OAKS Consulting Praha, Prague, Czech Republic. 9. Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic.
Abstract
Background/Aim: This study aimed at contributing to a better diagnosis of lung cancer by analyzing the patient's symptoms and their linkage to other characteristics. Patients and Methods: We analyzed the data of 3,322 patients from LUCAS (LUngCAncerfocuS) National Registry of the Czech Republic. Overall survival was assessed using the Kaplan-Meier method. Results: The most common symptoms were cough (47.5%), dyspnea (45.6%), pain (27.3%), and weight loss (25.7%). Among all patients, 16% were asymptomatic. We demonstrated the negative prognostic significance of increasing number of lung cancer symptoms, that was significant after adjustment for age, TNM stages, and performance status, and morphological types of the cancer. Conclusion: Monitoring the severity and type of symptoms in patients with lung cancer can help in the diagnostics of the disease and the estimation of prognosis. Copyright 2022, International Institute of Anticancer Research.
Background/Aim: This study aimed at contributing to a better diagnosis of lung cancer by analyzing the patient's symptoms and their linkage to other characteristics. Patients and Methods: We analyzed the data of 3,322 patients from LUCAS (LUngCAncerfocuS) National Registry of the Czech Republic. Overall survival was assessed using the Kaplan-Meier method. Results: The most common symptoms were cough (47.5%), dyspnea (45.6%), pain (27.3%), and weight loss (25.7%). Among all patients, 16% were asymptomatic. We demonstrated the negative prognostic significance of increasing number of lung cancer symptoms, that was significant after adjustment for age, TNM stages, and performance status, and morphological types of the cancer. Conclusion: Monitoring the severity and type of symptoms in patients with lung cancer can help in the diagnostics of the disease and the estimation of prognosis. Copyright 2022, International Institute of Anticancer Research.
Authors: F M Walter; G Rubin; C Bankhead; H C Morris; N Hall; K Mills; C Dobson; R C Rintoul; W Hamilton; J Emery Journal: Br J Cancer Date: 2015-03-31 Impact factor: 7.640