Literature DB >> 35394559

Tet Enzymes-Mediated DNA 5hmC Modification in Cerebral Ischemic and Hemorrhagic Injury.

Xiaohua Ma1,2, Bo Yang3, Xiaojing Li4, Zhigang Miao5,6.   

Abstract

5-Hydroxymethylcytosine (5hmC) has recently been found that plays an important role in many diseases; however, there are still few studies in the field of stroke. The purpose of this review is to introduce the influence and function of 5hmC in stroke, in order for more people can study it. In this review, we introduced the role of 5hmC in ischemia and hemorrhage stroke, and summarized the possible therapeutic prospects of 5hmC in stroke. In conclusion, we suggest that 5hmC may serve as a biomarker or therapeutic target for the treatment of stroke.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  5-Hydroxymethylcytosine; Methylation; Stroke; Tet

Mesh：

Substances：

Year:  2022        PMID： 35394559     DOI： 10.1007/s12640-022-00505-7

Source DB:  PubMed          Journal:  Neurotox Res        ISSN： 1029-8428            Impact factor:   3.911


  73 in total

1.  Ascorbate-induced generation of 5-hydroxymethylcytosine is unaffected by varying levels of iron and 2-oxoglutarate.

Authors:  Kevin M Dickson; Christopher B Gustafson; Juan I Young; Stephan Züchner; Gaofeng Wang
Journal:  Biochem Biophys Res Commun       Date:  2013-09-08       Impact factor: 3.575

2.  Perinatal acidosis and hypoxic-ischemic encephalopathy in preterm infants of 33 to 35 weeks' gestation.

Authors:  Lina F Chalak; Nancy Rollins; Michael C Morriss; Luc P Brion; Roy Heyne; Pablo J Sánchez
Journal:  J Pediatr       Date:  2011-10-26       Impact factor: 4.406

3.  Decreased TET2 gene expression during chronic myeloid leukemia progression.

Authors:  F Albano; L Anelli; A Zagaria; N Coccaro; A Minervini; A Russo Rossi; G Specchia
Journal:  Leuk Res       Date:  2011-07-27       Impact factor: 3.156

4.  TET1-Mediated Oxidation of 5-Formylcytosine (5fC) to 5-Carboxycytosine (5caC) in RNA.

Authors:  Maria Basanta-Sanchez; Rui Wang; Zhenzhen Liu; Xiaohan Ye; Minyong Li; Xiaodong Shi; Paul F Agris; Yubin Zhou; Yun Huang; Jia Sheng
Journal:  Chembiochem       Date:  2016-11-22       Impact factor: 3.164

5.  Epigenetic regulation of motor neuron cell death through DNA methylation.

Authors:  Barry A Chestnut; Qing Chang; Ann Price; Catherine Lesuisse; Margaret Wong; Lee J Martin
Journal:  J Neurosci       Date:  2011-11-16       Impact factor: 6.167

Review 6.  Molecular pathophysiology of cerebral hemorrhage: secondary brain injury.

Authors:  Jaroslaw Aronowski; Xiurong Zhao
Journal:  Stroke       Date:  2011-04-28       Impact factor: 7.914

7.  Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients.

Authors:  Leonidas Chouliaras; Diego Mastroeni; Elaine Delvaux; Andrew Grover; Gunter Kenis; Patrick R Hof; Harry W M Steinbusch; Paul D Coleman; Bart P F Rutten; Daniel L A van den Hove
Journal:  Neurobiol Aging       Date:  2013-04-09       Impact factor: 4.673

Review 8.  Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage.

Authors:  Martín Bustelo; Melinda Barkhuizen; Daniel L A van den Hove; Harry Wilhelm M Steinbusch; Martín A Bruno; C Fabián Loidl; Antonio W Danilo Gavilanes
Journal:  Front Neurol       Date:  2020-06-09       Impact factor: 4.003

9.  Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life.

Authors:  Zewen Chen; Lei Gong; Peng Zhang; Yong Li; Bailin Liu; Lubo Zhang; Jian Zhuang; Daliao Xiao
Journal:  Int J Biol Sci       Date:  2019-05-11       Impact factor: 6.580

10.  Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells.

Authors:  Kathryn Blaschke; Kevin T Ebata; Mohammad M Karimi; Jorge A Zepeda-Martínez; Preeti Goyal; Sahasransu Mahapatra; Angela Tam; Diana J Laird; Martin Hirst; Anjana Rao; Matthew C Lorincz; Miguel Ramalho-Santos
Journal:  Nature       Date:  2013-06-30       Impact factor: 49.962
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