| Literature DB >> 35387628 |
Zhang Yue1, Hang Liang1, Xigang Qin1, Yang Ge1, Nan Xiang1, Erpeng Liu2.
Abstract
BACKGROUND: Optimism-the generalized expectation that good things will happen-is a promising health asset. Mounting evidence indicates that there are specific associations between optimism and survival rates. However, for public health purposes, it is critical to consider whether the relationship between optimism and survival holds for older adults as a whole and to explore the role of health behaviors as potential mediators.Entities:
Keywords: Chinese elderly people; Follow-up study; Health behaviors; Mediating effect; Optimism; Survival
Mesh:
Year: 2022 PMID: 35387628 PMCID: PMC8988364 DOI: 10.1186/s12889-022-13090-3
Source DB: PubMed Journal: BMC Public Health ISSN: 1471-2458 Impact factor: 3.295
Fig. 1Flowchart describing sample selection
Fig. 2The mediation model proposed
Descriptive statistics of analytic variables at baseline (n = 13,370)
| Variable | Optimistic ( | Less optimistic ( | |||
|---|---|---|---|---|---|
| Gender | |||||
| Female | 3343 | 49.01 | 3837 | 58.59 | < 0.001 |
| Male | 3478 | 50.99 | 2712 | 41.41 | |
| Education level | |||||
| No formal education (illiterate) | 3498 | 51.28 | 4250 | 64.90 | < 0.001 |
| Primary school | 1711 | 25.08 | 1455 | 22.22 | |
| Junior high school | 874 | 12.81 | 505 | 7.71 | |
| Senior high school | 407 | 5.97 | 186 | 2.84 | |
| College or university graduate | 331 | 4.85 | 153 | 2.34 | |
| Marital status | |||||
| Married | 3084 | 45.21 | 1930 | 29.47 | < 0.001 |
| Single/divorced/widowed | 3737 | 54.79 | 4619 | 70.53 | |
| Residence | |||||
| Town | 3007 | 44.08 | 2411 | 36.81 | < 0.001 |
| Rural | 3814 | 55.92 | 4138 | 63.19 | |
| Co-residence with family members | |||||
| Yes | 5852 | 85.79 | 5078 | 77.54 | < 0.001 |
| No | 969 | 14.21 | 1471 | 22.46 | |
| Medical insurance | |||||
| Yes | 3722 | 54.57 | 2894 | 44.19 | < 0.001 |
| No | 3099 | 45.43 | 3655 | 55.81 | |
| Pension insurance | |||||
| Yes | 1747 | 25.61 | 918 | 14.02 | < 0.001 |
| No | 5074 | 74.39 | 5631 | 85.98 | |
| Mean | SD | Mean | SD | ||
| Health behaviors | 13.41 | 2.58 | 13.27 | 2.48 | < 0.001 |
| Age (years) | 83.31 | 11.50 | 86.06 | 10.67 | < 0.001 |
| Chronic diseases | 0.67 | 1.03 | 0.71 | 1.03 | 0.007 |
| ADL | 17.65 | 1.31 | 17.30 | 1.94 | < 0.001 |
| Decision-making power in the family | 3.89 | 1.17 | 3.39 | 1.17 | < 0.001 |
| Family economic status | 3.12 | 0.57 | 2.78 | 0.67 | < 0.001 |
| Numbers of children | 4.30 | 2.12 | 4.36 | 2.22 | 0.065 |
Abbreviations: ADL activities of daily living, SD standard deviation
P-values from t-tests (continuous variables) or chi-square tests (categorical variables)
Fig. 3Kaplan–Meier analysis of survival according to two categories of optimism
Hazard ratios of mortality by optimism over 10 years of follow-up
| Variable | Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|---|
| Optimism | ||||||
| Less optimistic | 1.00 | 1.00 | ||||
| Optimistic | 0.93 (0.89, 0.98) | 0.008 | 0.94 (0.89 − 0.99) | 0.014 | ||
| Health behaviors | 0.95 (0.94 − 0.96) | < 0.001 | ||||
| Age (years) | 1.06 (1.05 − 1.06) | < 0.001 | 1.06 (1.05 − 1.06) | < 0.001 | 1.06 (1.05 − 1.06) | < 0.001 |
| Gender | ||||||
| Female | 1.00 | 1.00 | ||||
| Male | 1.51 (1.43 − 1.60) | < 0.001 | 1.52 (1.43 − 1.61) | < 0.001 | 1.52 (1.44 − 1.61) | < 0.001 |
| Education level | ||||||
| No formal education (illiterate) | 1.00 | 1.00 | 1.00 | |||
| Primary school | 0.95 (0.89 − 1.02) | 0.136 | 0.95 (0.89 − 1.02) | 0.136 | 0.96 (0.90 − 1.03) | 0.275 |
| Junior high school | 0.87 (0.79 − 0.96) | 0.008 | 0.87 (0.79 − 0.97) | 0.009 | 0.89 (0.80 − 0.98) | 0.023 |
| Senior high school | 0.81 (0.70 − 0.94) | 0.006 | 0.81 (0.70 − 0.94) | 0.007 | 0.83 (0.72 − 0.97) | 0.020 |
| College or university graduate | 0.73 (0.61 − 0.88) | < 0.001 | 0.73 (0.61 − 0.88) | < 0.001 | 0.76 (0.63 − 0.91) | 0.002 |
| Marital status | ||||||
| Single/divorced/wid wed | 1.00 | 1.00 | 1.00 | |||
| Married | 0.85 (0.79 − 0.91) | < 0.001 | 0.85 (0.79 − 0.91) | < 0.001 | 0.85 (0.80 − 0.91) | < 0.001 |
| Residence | ||||||
| Rural | 1.00 | 1.00 | 1.00 | |||
| Town | 0.77 (0.73 − 0.81) | < 0.001 | 0.77 (0.73 − 0.82) | < 0.001 | 0.78 (0.74 − 0.82) | < 0.001 |
| Co-residence with family members | ||||||
| No | 1.00 | 1.00 | 1.00 | |||
| Yes | 1.09 (1.02 − 1.17) | 0.011 | 1.10 (1.03 − 1.18) | 0.006 | 1.10 (1.03 − 1.18) | 0.004 |
| Medical insurance | ||||||
| No | 1.00 | 1.00 | 1.00 | |||
| Yes | 0.37 (0.35 − 0.39) | < 0.001 | 0.37 (0.35 − 0.39) | < 0.001 | 0.37 (0.35 − 0.39) | < 0.001 |
| Pension insurance | ||||||
| No | 1.00 | 1.00 | 1.00 | |||
| Yes | 0.86 (0.79 − 0.93) | < 0.001 | 0.87 (0.80 − 0.94) | < 0.001 | 0.90 (0.83 − 0.98) | 0.010 |
| ADL | 0.96 (0.95 − 0.98) | < 0.001 | 0.96 (0.95 − 0.98) | < 0.001 | 0.97 (0.96 − 0.99) | < 0.001 |
| Chronic diseases | 1.03 (1.01 − 1.06) | 0.021 | 1.03 (1.00 − 1.06) | 0.032 | 1.03 (1.01 − 1.06) | 0.015 |
| Decision-making power in the family | 0.98 (0.96 − 1.00) | 0.040 | 0.98 (0.96 − 1.00) | 0.116 | 0.99 (0.97 − 1.01) | 0.397 |
| Family economic status | 0.98 (0.94 − 1.02) | 0.347 | 0.99 (0.96 − 1.03) | 0.765 | 1.00 (0.96 − 1.04) | 0.835 |
| Number of children | 1.03 (1.02 − 1.04) | < 0.001 | 1.03 (1.02 − 1.04) | < 0.001 | 1.03 (1.02 − 1.04) | < 0.001 |
Abbreviations: ADL activities of daily living, HR hazard ratio, CI confidence interval
Analysis of mediating effect of health behaviors
| Model 4 (Outcome: mortality) | |||||
| Optimism | c (Total effect) | -0.070 | (-0.12 − -0.02) | 0.008 | 100.00 |
| Model 5 (Outcome: health behaviors) | |||||
| Optimism | a | 0.086 | (0.07 − 0.14) | 0.030 | – |
| Model 6 (Outcome: mortality) | |||||
| Optimism | c’ (Direct effect) | -0.065 | (-0.09 − -0.05) | 0.014 | 92.85 |
| Health behaviors | b | -0.053 | (-0.09 − -0.05) | < 0.001 | – |
| Mediating effect | a x b (Indirect effect) | -0.005 | (0.03 − 0.09) | – | 7.15 |
Note: CI Confidence Interval. Model 4, optimism → mortality; Model 5, optimism → health behaviors; Model 6, optimism, health behaviors → mortality
#Overall test of association adjusted for gender, age, education level, marital status, residence, ADL, chronic diseases, decision-making power in the family, family economic status, number of children, co-residence with family members, medical insurance and pension insurance. The effects of covariates were omitted