Khadija El Aoufy1, Cosimo Bruni1, Laura Rasero2, Marco Matucci Cerinic1, Daniel Eric Furst1,3,4. 1. Department of Experimental and Clinical Medicine, AOUC, University of Florence, Italy. 2. Department of Health Science, AOUC, University of Florence, Italy. 3. Division of Rheumatology, UCLA, Los Angeles, CA, USA. 4. University of Washington, Seattle, WA, USA.
Abstract
Objectives: The aim of this study is to ascertain systemic sclerosis patients' preferences regarding the formulations of the medications they use. Methods: We undertook questionnaires and interviews aimed at understanding systemic sclerosis patients' preferences with respect to the medications they used. Results: Among 160 systemic sclerosis patients, we found that the majority does not have difficulty taking their medication. However, preferences were identified (81.25% - 65/80 - preferred oral meds and 47.50% - 38/80 - disliked rectal/vaginal meds), as well as some systemic sclerosis patients have significant difficulties using their medications. In fact, factors such as swallowing and fine finger motion difficulties were frequent, while intravenous/intramuscular/subcutaneous medicines were usually not preferred because they are felt as inconvenient (intravenous = 33.4% and subcutaneous/intramuscular = 10%) or painful (intravenous = 37.50% and subcutaneous/intramuscular = 10%). Conclusion: Most systemic sclerosis patients are able to take their medication despite having some difficulties. However, as there were clear preferences, we could improve patients' adherence to drug therapy if taking these preferences into account.
Objectives: The aim of this study is to ascertain systemic sclerosis patients' preferences regarding the formulations of the medications they use. Methods: We undertook questionnaires and interviews aimed at understanding systemic sclerosis patients' preferences with respect to the medications they used. Results: Among 160 systemic sclerosis patients, we found that the majority does not have difficulty taking their medication. However, preferences were identified (81.25% - 65/80 - preferred oral meds and 47.50% - 38/80 - disliked rectal/vaginal meds), as well as some systemic sclerosis patients have significant difficulties using their medications. In fact, factors such as swallowing and fine finger motion difficulties were frequent, while intravenous/intramuscular/subcutaneous medicines were usually not preferred because they are felt as inconvenient (intravenous = 33.4% and subcutaneous/intramuscular = 10%) or painful (intravenous = 37.50% and subcutaneous/intramuscular = 10%). Conclusion: Most systemic sclerosis patients are able to take their medication despite having some difficulties. However, as there were clear preferences, we could improve patients' adherence to drug therapy if taking these preferences into account.
Authors: Candace H Feldman; Jinoos Yazdany; Hongshu Guan; Daniel H Solomon; Karen H Costenbader Journal: Arthritis Care Res (Hoboken) Date: 2015-12 Impact factor: 4.794
Authors: Frank van den Hoogen; Dinesh Khanna; Jaap Fransen; Sindhu R Johnson; Murray Baron; Alan Tyndall; Marco Matucci-Cerinic; Raymond P Naden; Thomas A Medsger; Patricia E Carreira; Gabriela Riemekasten; Philip J Clements; Christopher P Denton; Oliver Distler; Yannick Allanore; Daniel E Furst; Armando Gabrielli; Maureen D Mayes; Jacob M van Laar; James R Seibold; Laszlo Czirjak; Virginia D Steen; Murat Inanc; Otylia Kowal-Bielecka; Ulf Müller-Ladner; Gabriele Valentini; Douglas J Veale; Madelon C Vonk; Ulrich A Walker; Lorinda Chung; David H Collier; Mary Ellen Csuka; Barri J Fessler; Serena Guiducci; Ariane Herrick; Vivien M Hsu; Sergio Jimenez; Bashar Kahaleh; Peter A Merkel; Stanislav Sierakowski; Richard M Silver; Robert W Simms; John Varga; Janet E Pope Journal: Ann Rheum Dis Date: 2013-11 Impact factor: 19.103
Authors: Bart J F van den Bemt; Frank H J van den Hoogen; Bart Benraad; Yechiel A Hekster; Piet L C M van Riel; Wim van Lankveld Journal: J Rheumatol Date: 2009-09-01 Impact factor: 4.666
Authors: Cosimo Bruni; Sebastian Heidenreich; Ashley Duenas; Anna-Maria Hoffmann-Vold; Armando Gabrielli; Yannick Allanore; Emmanuel Chatelus; Jörg H W Distler; Eric Hachulla; Vivien M Hsu; Nicolas Hunzelmann; Dinesh Khanna; Marie-Elise Truchetet; Ulrich A Walker; Margarida Alves; Nils Schoof; Lesley Ann Saketkoo; Oliver Distler Journal: Rheumatology (Oxford) Date: 2022-10-06 Impact factor: 7.046