| Literature DB >> 3538501 |
R L Gupta, D K Dey, T R Juneja.
Abstract
The mutagenic potential of 4-nitrodiphenyl ether (NDE) an intermediate of herbicides and an anthelmintic drug, and its reduced products (-NO, -NHOH) were investigated in the Ames test. All the three compounds were potent direct-acting base-pair and frameshift mutagens with activity order -NHOH greater than -NO greater than -NO2. The -NHOH compound has been considered to be the penultimate/ultimate mutagen.Entities:
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Year: 1986 PMID： 3538501 DOI： 10.1016/0378-4274(86)90140-2
Source DB: PubMed Journal: Toxicol Lett ISSN： 0378-4274 Impact factor: 4.372