Literature DB >> 35384479

[Follow-up of testicular germ cell tumors-historical aspects and current recommendations].

Klaus-Peter Dieckmann1, Christian Guido Ruf2, Raphael Gübitz3, Christian Wülfing4, Friedemann Zengerling5.   

Abstract

Systematic follow-up examinations of patients cured of testicular cancer first gained attention by caregivers in the 1980s only after the management of the disease had significantly been improved by the introduction of cisplatin-based chemotherapy and almost synchronously, by the implementation of computerized tomography (CT) and serum tumor markers. Follow-up involves three aims: early diagnosis of recurrence, detection of treatment-related toxicity, and detection of secondary diseases. As the clinical presentation of testicular cancer is very heterogeneous, there is no uniform follow-up for the disease. Instead, risk-adapted follow-up schedules are required. Since the release of the German AWMF S3 guideline for the management of testicular cancer in 2019, high level evidence has accumulated for the noninferiority of magnetic resonance imaging (MRI) to CT with regard to abdominal imaging. Therefore, it is appropriate to modify the recommendations for follow-up given in the 2019 issue of the S3 guidelines. The modifications recommended herein relate to three issues: (1) Only three risk groups (instead of formerly four) are identified, i.e., seminoma (all stages); nonseminoma clinical stage 1b (i.e., pT2, with lymphovascular invasion) on surveillance; nonseminoma all other stages. All patients cured from poor risk disease or from relapses require individual follow-up schedules not included in the recommendations tabulated herein. (2) CT and abdominal sonography are replaced by MRI. (3) Chest X‑ray imaging during follow-up of seminoma patients is no longer recommended.
© 2022. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Entities:  

Keywords:  Cancer relapse; Chemotherapy; Magnetic resonance imaging; Tumor markers; Tumor size

Mesh:

Year:  2022        PMID: 35384479     DOI: 10.1007/s00120-022-01815-6

Source DB:  PubMed          Journal:  Urologe A        ISSN: 0340-2592            Impact factor:   0.639


  38 in total

1.  Prognostic factors for tumor recurrence in patients with clinical stage I seminoma undergoing surveillance-A systematic review.

Authors:  Friedemann Zengerling; Frank Kunath; Katrin Jensen; Christian Ruf; Stefanie Schmidt; Annabel Spek
Journal:  Urol Oncol       Date:  2017-07-13       Impact factor: 3.498

2.  [Risk-guided after-care of testicular tumor].

Authors:  K H Schölermann; R Dettmann; M Hartmann
Journal:  Urologe A       Date:  1996-07       Impact factor: 0.639

3.  [Results of close testicular tumor after-care].

Authors:  K Erpenbach; W Derschum; M Reis; H von Vietsch
Journal:  Urologe A       Date:  1990-03       Impact factor: 0.639

Review 4.  [Aftercare in testicular cancer is worthwhile. Recurrences are curable].

Authors:  T S Pottek; K-P Dieckmann
Journal:  Urologe A       Date:  2005-09       Impact factor: 0.639

5.  Efficacy of routine follow-up after first-line treatment for testicular cancer.

Authors:  J R Spermon; J A Witjes; L A L M Kiemeney
Journal:  World J Urol       Date:  2004-09-21       Impact factor: 4.226

6.  [The Munich follow-up program in advanced non-seminoma testicular tumors. Benefits and costs].

Authors:  C Clemm; W E Berdel; R Hartenstein; J Nisenbaum; U Fink; J Rastetter; W Wilmanns
Journal:  Dtsch Med Wochenschr       Date:  1986-08-01       Impact factor: 0.628

Review 7.  Recommendations of follow-up after treatment of germ cell tumors.

Authors:  G Varuni Kondagunta; Joel Sheinfeld; Robert J Motzer
Journal:  Semin Oncol       Date:  2003-06       Impact factor: 4.929

8.  Cost-effective follow-up of the cancer patient. Time for a new look.

Authors:  B Eiseman; A S Feiner
Journal:  Postgrad Med       Date:  1988-01       Impact factor: 3.840

9.  Sentinel node biopsy in clinical stage I testicular cancer enables early detection of occult metastatic disease.

Authors:  Joost M Blok; J Martijn Kerst; Erik Vegt; Oscar R Brouwer; Richard P Meijer; J L H Ruud Bosch; Axel Bex; Henk G van der Poel; Simon Horenblas
Journal:  BJU Int       Date:  2019-03-28       Impact factor: 5.588

10.  Evidence-based pragmatic guidelines for the follow-up of testicular cancer: optimising the detection of relapse.

Authors:  N J van As; D C Gilbert; J Money-Kyrle; D Bloomfield; S Beesley; D P Dearnaley; A Horwich; R A Huddart
Journal:  Br J Cancer       Date:  2008-06-17       Impact factor: 7.640

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