Xuan Liao1,2, Mei-Jie Wang2, Qing-Qing Tan1,2, Chang-Jun Lan3,4. 1. Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, 1 Mao Yuan South Road, Nanchong, Sichuan, China. 2. Department of Ophthalmology and Optometry, North Sichuan Medical College, Nanchong, Sichuan, China. 3. Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, 1 Mao Yuan South Road, Nanchong, Sichuan, China. eyelanchangjun@163.com. 4. Department of Ophthalmology and Optometry, North Sichuan Medical College, Nanchong, Sichuan, China. eyelanchangjun@163.com.
Abstract
PURPOSE: To evaluate the repeatability of wavefront aberration measurements and the correlation between corneal aberration and pupil size in normal eyes using a wavefront-based autorefractor (i.ProfilerPlus; Carl Zeiss Vision, Germany). METHODS: A prospective cross-sectional study. Wavefront aberrations, including spherical aberration (SA) (Z40), coma (Z3-1, Z31), trefoil (Z3-3, Z33) and total higher-order aberrations (tHOA), were measured at different pupil diameters. The repeatability was evaluated using one-way ANOVA method, and statistical indicators including within-subject standard deviation (Sw), test-retest repeatability (TRT), and intra-class correlation coefficient (ICC). The correlations between corneal aberrations and pupil sizes were evaluated by Pearson correlation analysis. RESULTS: A total of 96 healthy young volunteers were enrolled. Corneal and ocular higher-order aberrations (HOA) measured by i.Profiler showed Sw < 0.01 μm, TRT < 0.10 μm, ICC > 0.90. There was a linear positive correlation between the corneal HOA and pupil size. The correlation coefficient between SA and tHOA was the largest (r = 0.996, P < 0.001). CONCLUSIONS: The measurements of wavefront aberrations by i.Profiler are highly repeatable. Corneal HOA was significantly dependent on pupil size. SA was the most influential aberration for visual quality in this study.
PURPOSE: To evaluate the repeatability of wavefront aberration measurements and the correlation between corneal aberration and pupil size in normal eyes using a wavefront-based autorefractor (i.ProfilerPlus; Carl Zeiss Vision, Germany). METHODS: A prospective cross-sectional study. Wavefront aberrations, including spherical aberration (SA) (Z40), coma (Z3-1, Z31), trefoil (Z3-3, Z33) and total higher-order aberrations (tHOA), were measured at different pupil diameters. The repeatability was evaluated using one-way ANOVA method, and statistical indicators including within-subject standard deviation (Sw), test-retest repeatability (TRT), and intra-class correlation coefficient (ICC). The correlations between corneal aberrations and pupil sizes were evaluated by Pearson correlation analysis. RESULTS: A total of 96 healthy young volunteers were enrolled. Corneal and ocular higher-order aberrations (HOA) measured by i.Profiler showed Sw < 0.01 μm, TRT < 0.10 μm, ICC > 0.90. There was a linear positive correlation between the corneal HOA and pupil size. The correlation coefficient between SA and tHOA was the largest (r = 0.996, P < 0.001). CONCLUSIONS: The measurements of wavefront aberrations by i.Profiler are highly repeatable. Corneal HOA was significantly dependent on pupil size. SA was the most influential aberration for visual quality in this study.
Authors: Franziska G Rauscher; Heike Lange; Maryam Yahiaoui-Doktor; Helmut Tegetmeyer; Ina Sterker; Andreas Hinz; Siegfried Wahl; Peter Wiedemann; Arne Ohlendorf; Ralf Blendowske Journal: Optom Vis Sci Date: 2019-11 Impact factor: 1.973