Literature DB >> 35381377

Design of a clinical trial to isolate the experience of food insecurity and elucidate the biological mechanisms of risk for childhood health outcomes.

E Whitney Evans1, Elissa Jelalian2, Shira Dunsiger3, Douglas Villalta4, Audrey Tyrka5.   

Abstract

BACKGROUND: Food insecurity affects one in seven households with children in the United States, disproportionately impacts households headed by women and minorities, and is associated with childhood comorbidities, including obesity. While food insecurity likely contributes to poor health through its effect on diet, such a simplistic understanding likely obscures the effects of poverty-related stress and other Adverse Childhood Experiences, on metabolic health.
METHODS: Over two summers, 100 children, ages 8-12 years, will be recruited from low-income households in an urban, Rhode Island community, to participate in an 8-week trial designed to isolate the experience of food insecurity. Summer represents a natural risk period of food insecurity in children, such that children will be randomized to receive weekly shipments of five breakfast and lunch meals that mimic school meals or to experience the likely onset of summertime food insecurity and receive a weekly newsletter on community resources that is not expected to affect food insecurity. Through assessment visits at baseline, mid-summer and end of summer, we will examine group differences in change in diet quality, biomarkers of Metabolic Syndrome, inflammation, and stress, BMI z-scores, and child measures of behavior and anxiety and depression symptoms. We will also explore the impact of caregiver mood and stress on the health effects of food insecurity.
CONCLUSIONS: Findings stand to clarify the mechanisms by which food insecurity affects child health outcomes and to inform how to best address food insecurity in the context of poverty-related stress. TRIAL REGISTRATION: This trial has been registered at ClinicalTrials.gov (NCT04968496).
Copyright © 2022 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adverse childhood experiences; Childhood obesity; Food insecurity

Mesh:

Year:  2022        PMID: 35381377      PMCID: PMC9156564          DOI: 10.1016/j.cct.2022.106751

Source DB:  PubMed          Journal:  Contemp Clin Trials        ISSN: 1551-7144            Impact factor:   2.261


  44 in total

1.  Childhood origins of adult health: a basis for life-course health policy.

Authors:  Christopher B Forrest; Anne W Riley
Journal:  Health Aff (Millwood)       Date:  2004 Sep-Oct       Impact factor: 6.301

2.  Changes in weight over the school year and summer vacation: results of a 5-year longitudinal study.

Authors:  Jennette P Moreno; Craig A Johnston; Deborah Woehler
Journal:  J Sch Health       Date:  2013-07       Impact factor: 2.118

3.  Adverse childhood experiences: Evidence for screening beyond preventive visits.

Authors:  Naomi N Duke; Iris W Borowsky
Journal:  Child Abuse Negl       Date:  2018-05-26

4.  Weekly change in mindfulness and perceived stress in a mindfulness-based stress reduction program.

Authors:  Ruth A Baer; James Carmody; Matthew Hunsinger
Journal:  J Clin Psychol       Date:  2012-05-23

5.  Ecological Momentary Assessment and Mood Disorders in Children and Adolescents: a Systematic Review.

Authors:  Itziar Baltasar-Tello; Carolina Miguélez-Fernández; Inmaculada Peñuelas-Calvo; Juan J Carballo
Journal:  Curr Psychiatry Rep       Date:  2018-08-01       Impact factor: 5.285

6.  Agreement between child and parent reports of 10- to 12-year-old children's meal pattern and intake of snack foods.

Authors:  C Persson Osowski; C Fjellström; U Olsson; H Göranzon
Journal:  J Hum Nutr Diet       Date:  2011-05-25       Impact factor: 3.089

Review 7.  Poverty grown up: how childhood socioeconomic status impacts adult health.

Authors:  Kathleen Conroy; Megan Sandel; Barry Zuckerman
Journal:  J Dev Behav Pediatr       Date:  2010 Feb-Mar       Impact factor: 2.225

Review 8.  Adipokines in inflammation and metabolic disease.

Authors:  Noriyuki Ouchi; Jennifer L Parker; Jesse J Lugus; Kenneth Walsh
Journal:  Nat Rev Immunol       Date:  2011-01-21       Impact factor: 53.106

9.  Children Receiving Free or Reduced-Price School Lunch Have Higher Food Insufficiency Rates in Summer.

Authors:  Jin Huang; Ellen Barnidge; Youngmi Kim
Journal:  J Nutr       Date:  2015-07-22       Impact factor: 4.798

10.  Food insecurity is not associated with lower energy intakes.

Authors:  Claire A Zizza; Patricia A Duffy; Shirley A Gerrior
Journal:  Obesity (Silver Spring)       Date:  2008-05-29       Impact factor: 5.002

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