Literature DB >> 35380269

Clear Cornea Femto DALK: a novel technique for performing deep anterior lamellar keratoplasty.

Georg Gerten1,2,3, Uwe Oberheide4,5, Philipp Thiée6,4,5.   

Abstract

PURPOSE: A new femtosecond laser assisted deep anterior lamellar keratoplasty technique (Clear Cornea Femto DALK or CCF DALK) can be performed with less technical challenges compared to conventional procedures. This paper reports on a preliminary case series to evaluate the technique.
METHOD: First, through a clear cornea approach, Descemet's membrane (DM) is completely separated from posterior stroma by injection of balanced salt solution/viscoelastic substance through a special cannula inserted into the deep stroma and positioned right above the DM without perforating. The injection creates a liquid chamber that detaches the DM while preserving a reasonably transparent corneal stroma. Afterwards, a complete posterior/anterior trephination of the stroma, from the liquid chamber to the epithelium, is done using a femtosecond laser system under optical coherence tomography control.
RESULTS: This technique was successfully performed in a preliminary series of 10 eyes/10 patients. All patients had the DM completely bared and kept their own endothelial cell population with minimal cell loss (< 15%) after 6 months. Postoperative interface reaction was minimal, and no immune reactions were observed thus far.
CONCLUSION: Clear Cornea Femto DALK is a promising alternative to previous Femto DALK procedures with good acceptance of the tissue seen to date.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Clear cornea Femto DALK; Deep anterior lamellar keratoplasty; Descemet’s membrane; Femtosecond laser; Liquid bubble; Stromal disease; Tissue dissection

Mesh:

Year:  2022        PMID: 35380269     DOI: 10.1007/s00417-022-05582-0

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.535


  2 in total

1.  Changing trends in corneal graft surgery: a ten-year review.

Authors:  Ugo de Sanctis; Camilla Alovisi; Luigi Bauchiero; Guido Caramello; Gianfranco Girotto; Claudio Panico; Luisa Vinai; Federico Genzano; Antonio Amoroso; Federico Grignolo
Journal:  Int J Ophthalmol       Date:  2016-01-18       Impact factor: 1.779

2.  Real-time optical coherence tomography-guided femtosecond laser sub-Bowman keratomileusis on human donor eyes.

Authors:  Omid Kermani; Will Fabian; Holger Lubatschowski
Journal:  Am J Ophthalmol       Date:  2008-04-24       Impact factor: 5.258

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.