Literature DB >> 35378511

Case Report: Isoniazid-Associated Delirium in an Elderly Female with Spinal Tuberculosis.

Upinder Kaur1, Rohit Singh2, Amit Singh1, Sankha Shubhra Chakrabarti2.   

Abstract

Isoniazid is an important component of first-line antitubercular therapy. The drug at its therapeutic dose is known to cause hepatitis and peripheral neuropathy. The association of isoniazid with pure delirium is rare. Here, we present an interesting case of new-onset delirium associated with isoniazid in an elderly female with spinal tuberculosis. Remarkable improvement was noticed in the patient following drug discontinuation and pyridoxine augmentation.

Entities:  

Year:  2022        PMID: 35378511      PMCID: PMC9128681          DOI: 10.4269/ajtmh.21-1282

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   3.707


  7 in total

1.  Isoniazid-associated psychosis.

Authors:  Agnieszka E Witkowski; Catherine G Manabat; James A Bourgeois
Journal:  Gen Hosp Psychiatry       Date:  2007 Jan-Feb       Impact factor: 3.238

2.  A case of isoniazid-induced delirium.

Authors:  Benedetta Demartini; Maurizia Camisasca; Massimo Zuin; Orsola Gambini
Journal:  J Neuropsychiatry Clin Neurosci       Date:  2013       Impact factor: 2.198

3.  Sustained drug-induced elevation of brain GABA in the rat.

Authors:  T L Perry; S Hansen
Journal:  J Neurochem       Date:  1973-11       Impact factor: 5.372

4.  Isoniazid Induced Metabolic Acidosis and Renal Dysfunction in an Elderly Patient with Chronic Renal Disease.

Authors:  Upinder Kaur; Sankha S Chakrabarti; Indrajeet S Gambhir
Journal:  Curr Drug Saf       Date:  2016

5.  Isoniazid induced encephalopathy in dialysis patients.

Authors:  W C Cheung; C Y Lo; W K Lo; M Ip; I K Cheng
Journal:  Tuber Lung Dis       Date:  1993-04

6.  Acute Psychosis after Recent Isoniazid Initiation.

Authors:  Sidharth Arya; Gagandeep Sukhija; Harpreet Singh
Journal:  J Clin Diagn Res       Date:  2015-06-01

7.  Thrombocytopenia due to rifampicin.

Authors:  Ramakant Dixit; Jacob George; Arun Kumar Sharma
Journal:  Lung India       Date:  2012-01
  7 in total

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