Literature DB >> 35377072

Heterotopic ossification in primary total hip arthroplasty: risk factor analysis.

Alessandro Aprato1, Simone Cambursano2, Stefano Artiaco2, Stefano Bevilacqua2, Paolo Catalani2, Alessandro Massè2.   

Abstract

BACKGROUND: Aim is to identify if age, sex, type of posterolateral approach (mini vs standard), surgical time and time from surgery to drainage removal were independent risk factors for heterotopic ossifications after total hip arthroplasty.
MATERIALS AND METHODS: Patients who underwent a THA with posterolateral approach during a 15 years period were included. The exclusion criteria were absence of X-rays follow-up or HO prophylaxis protocol adoption. The following data were collected: age, sex, type of approach (classical/minimal-invasive), surgical time, time from surgery to drainage removal. Two orthopedic surgeons independently reviewed the 2 years follow-up X-rays and classified the HO according to Brooker classification. Severe HO was defined if HO were classified as major than grade 2. Correlation between severe HO and risk factor has been tested with multivariable analysis.
RESULTS: About 1225 patients were included: mean age of 63.8 years, 504 were men. HO were found in 67.6%. Men showed higher severe HO rate than woman (44.1% vs 29.1%, p = 0.001). Patients older than 65 years showed higher severe HO rate (30.3% vs 39.9%, p = 0.002). Standard posterolateral approach was performed in 75.4% and severe HO rate was 32.8% versus 27.1% in those treated with the minimally invasive approach (p = 0.067). In 75.6% of cases surgery lasted less than 90 min and this group showed a severe HO rate in 29.1%, while patient with longer surgical time showed a rate of 35.7% (p = 0.033). In 47.4% of patients, the drainage was removed in the first post-operative day, in this group severe HO rate was significantly lower than the others: 24.8 versus 36.2% (p = 0.001). DISCUSSION: Male sex, age older than 65 years, surgical time longer than 90 min and delayed drainage removal are risk factors for severe HO. Patients with one or more of those risk factors should be identified as good candidates for HO prophylaxis.
© 2022. The Author(s).

Entities:  

Keywords:  Brooker classification; Heterotopic ossification; Hip arthroplasty outcomes; Total hip arthroplasty

Year:  2022        PMID: 35377072     DOI: 10.1007/s00590-022-03244-9

Source DB:  PubMed          Journal:  Eur J Orthop Surg Traumatol        ISSN: 1633-8065


  20 in total

Review 1.  Heterotopic ossification after hip and knee arthroplasty: risk factors, prevention, and treatment.

Authors:  Richard Iorio; William L Healy
Journal:  J Am Acad Orthop Surg       Date:  2002 Nov-Dec       Impact factor: 3.020

Review 2.  The operation of the century: total hip replacement.

Authors:  Ian D Learmonth; Claire Young; Cecil Rorabeck
Journal:  Lancet       Date:  2007-10-27       Impact factor: 79.321

3.  Complications of Total Hip Arthroplasty: Standardized List, Definitions, and Stratification Developed by The Hip Society.

Authors:  William L Healy; Richard Iorio; Andrew J Clair; Vincent D Pellegrini; Craig J Della Valle; Keith R Berend
Journal:  Clin Orthop Relat Res       Date:  2016-02       Impact factor: 4.176

Review 4.  Incidence and risk factors for heterotopic ossification after total hip arthroplasty: a meta-analysis.

Authors:  Yanbin Zhu; Fei Zhang; Wei Chen; Qi Zhang; Song Liu; Yingze Zhang
Journal:  Arch Orthop Trauma Surg       Date:  2015-07-09       Impact factor: 3.067

5.  Effect of heterotopic ossification on hip range of motion and clinical outcome.

Authors:  George I Vasileiadis; Derek F Amanatullah; Jeremy R Crenshaw; Michael J Taunton; Kenton R Kaufman
Journal:  J Arthroplasty       Date:  2014-10-02       Impact factor: 4.757

6.  Heterotopic ossification in total hip arthroplasty: the significance for clinical outcome.

Authors:  S Eggli; J Rodriguez; R Ganz
Journal:  Acta Orthop Belg       Date:  2000-04       Impact factor: 0.500

7.  Heterotopic Ossification in Primary Total Hip Arthroplasty Using the Direct Anterior vs Direct Lateral Approach.

Authors:  Pouya Alijanipour; Ripal P Patel; Tejal U Naik; Javad Parvizi
Journal:  J Arthroplasty       Date:  2016-11-22       Impact factor: 4.757

8.  Prevention of heterotopic ossification in high-risk patients with total hip arthroplasty: the experience of a combined therapeutic protocol.

Authors:  Emilios E Pakos; Evita J Pitouli; Pericles G Tsekeris; Vasiliki Papathanasopoulou; Kosmas Stafilas; Theodore H Xenakis
Journal:  Int Orthop       Date:  2006-02-16       Impact factor: 3.075

Review 9.  Heterotopic Ossification: A Challenging Complication of Total Hip Arthroplasty: Risk Factors, Diagnosis, Prophylaxis, and Treatment.

Authors:  Paweł Łęgosz; Maciej Otworowski; Aleksandra Sibilska; Krzysztof Starszak; Daniel Kotrych; Adam Kwapisz; Marek Synder
Journal:  Biomed Res Int       Date:  2019-04-16       Impact factor: 3.411

10.  Heterotopic Ossification in Primary Total Hip Arthroplasty: which is the role of drainage?

Authors:  Paolo Di Benedetto; Andrea Zangari; Stefano Magnanelli; Vanni Cainero; Alessandro Beltrame; Renato Gisonni; Araldo Causero
Journal:  Acta Biomed       Date:  2019-01-10
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