Literature DB >> 3537648

Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D.

P Goldberg, M C Fleming, E H Picard.   

Abstract

A group of young patients having multiple sclerosis was treated with dietary supplements containing calcium, magnesium and vitamin D for a period of one to two years. The experimental design employed self-pairing: the response of each patient was compared with his/her own case history as control. The number of exacerbations observed during the program was less than one half the number expected from case histories. No side effects were apparent. The dietary regimen may offer a new means of controlling the exacerbation rate in MS, at least for younger patients. The results tend to support a theory of MS which states that calcium and magnesium are important in the development, structure and stability of myelin.

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Year:  1986        PMID: 3537648     DOI: 10.1016/0306-9877(86)90010-1

Source DB:  PubMed          Journal:  Med Hypotheses        ISSN: 0306-9877            Impact factor:   1.538


  54 in total

Review 1.  Does vitamin D affect risk of developing autoimmune disease?: a systematic review.

Authors:  Martin A Kriegel; JoAnn E Manson; Karen H Costenbader
Journal:  Semin Arthritis Rheum       Date:  2010-11-02       Impact factor: 5.532

Review 2.  Mycobacterium tuberculosis, autoimmunity, and vitamin D.

Authors:  Yinon Shapira; Nancy Agmon-Levin; Yehuda Shoenfeld
Journal:  Clin Rev Allergy Immunol       Date:  2010-04       Impact factor: 8.667

3.  Impact of High-Dose Vitamin D3 Supplementation in Patients with Crohn's Disease in Remission: A Pilot Randomized Double-Blind Controlled Study.

Authors:  Neeraj Narula; Mohan Cooray; Rebecca Anglin; Zack Muqtadir; Alisha Narula; John K Marshall
Journal:  Dig Dis Sci       Date:  2016-12-14       Impact factor: 3.199

Review 4.  [Vitamin D and multiple sclerosis : the role for risk of disease and treatment].

Authors:  A Döring; F Paul; J Dörr
Journal:  Nervenarzt       Date:  2013-02       Impact factor: 1.214

5.  Calcium intervention ameliorates experimental model of multiple sclerosis.

Authors:  Dariush Haghmorad; Mohammad B Mahmoudi; Mahmoud Mahmoudi; Shahrzad Z T Rab; Maryam Rastin; Hamid Shegarfi; Gholamreza Azizi; Abbas Mirshafiey
Journal:  Oman Med J       Date:  2014-05

Review 6.  The effect of melanism and vitamin D synthesis on the incidence of autoimmune disease.

Authors:  Netta Shoenfeld; Howard Amital; Yehuda Shoenfeld
Journal:  Nat Clin Pract Rheumatol       Date:  2009-02

7.  Dietary patterns in clinical subtypes of multiple sclerosis: an exploratory study.

Authors:  Geeta S M Ramsaransing; Sanne A Mellema; Jacques De Keyser
Journal:  Nutr J       Date:  2009-08-10       Impact factor: 3.271

8.  Contribution of vitamin D insufficiency to the pathogenesis of multiple sclerosis.

Authors:  Charles Pierrot-Deseilligny; Jean-Claude Souberbielle
Journal:  Ther Adv Neurol Disord       Date:  2013-03       Impact factor: 6.570

Review 9.  Clinical implications of a possible role of vitamin D in multiple sclerosis.

Authors:  Charles Pierrot-Deseilligny
Journal:  J Neurol       Date:  2009-04-28       Impact factor: 4.849

10.  Evidence for genetic regulation of vitamin D status in twins with multiple sclerosis.

Authors:  Sarah-Michelle Orton; Andrew P Morris; Blanca M Herrera; Sreeram V Ramagopalan; Matthew R Lincoln; Michael J Chao; Reinhold Vieth; A Dessa Sadovnick; George C Ebers
Journal:  Am J Clin Nutr       Date:  2008-08       Impact factor: 7.045

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