| Literature DB >> 35373222 |
Shorabuddin Syed1, Adam Jackson Angel2, Hafsa Bareen Syeda3, Carole France Jennings4, Joseph VanScoy5, Mahanazuddin Syed1, Melody Greer1, Sudeepa Bhattacharyya6, Meredith Zozus7, Benjamin Tharian8, Fred Prior1.
Abstract
Colonoscopy is a screening and diagnostic procedure for detection of colorectal carcinomas with specific quality metrics that monitor and improve adenoma detection rates. These quality metrics are stored in disparate documents i.e., colonoscopy, pathology, and radiology reports. The lack of integrated standardized documentation is impeding colorectal cancer research. Clinical concept extraction using Natural Language Processing (NLP) and Machine Learning (ML) techniques is an alternative to manual data abstraction. Contextual word embedding models such as BERT (Bidirectional Encoder Representations from Transformers) and FLAIR have enhanced performance of NLP tasks. Combining multiple clinically-trained embeddings can improve word representations and boost the performance of the clinical NLP systems. The objective of this study is to extract comprehensive clinical concepts from the consolidated colonoscopy documents using concatenated clinical embeddings. We built high-quality annotated corpora for three report types. BERT and FLAIR embeddings were trained on unlabeled colonoscopy related documents. We built a hybrid Artificial Neural Network (h-ANN) to concatenate and fine-tune BERT and FLAIR embeddings. To extract concepts of interest from three report types, 3 models were initialized from the h-ANN and fine-tuned using the annotated corpora. The models achieved best F1-scores of 91.76%, 92.25%, and 88.55% for colonoscopy, pathology, and radiology reports respectively.Entities:
Keywords: Clinical Concept Extraction; Colonoscopy; Deep Learning; Natural Language Processing; Word Embeddings
Year: 2022 PMID: 35373222 PMCID: PMC8970464 DOI: 10.5220/0010903300003123
Source DB: PubMed Journal: Biomed Eng Syst Technol Int Jt Conf BIOSTEC Revis Sel Pap