Literature DB >> 35371727

Scurvy in the Modern World: Extinct or Not?

Fnu Amisha1, Sai Nikhila Ghanta1, Amudha Kumar1, Tyler Fugere1, Paras Malik2, Sunilkumar Kakadia3.   

Abstract

Scurvy is a nutritional disorder caused by vitamin C deficiency. It was a notorious disease in the ancient world, especially among the sailors, and is of rare occurrence in contemporary, developed countries due to increased access and advancement in nutrition services. Scurvy primarily affects the skin and soft tissue, presenting with a myriad of clinical manifestations ranging from musculoskeletal to bleeding-related complaints and even sudden death in later stages. In this article, we present the case of an elderly female with scurvy-related weakness and gait instability leading to mechanical falls, easy bruising, fatigue, and petechial rash. She had improvement in her constitutional symptoms after the initiation of vitamin C supplements. This case reinforces the need to consider scurvy as one of the differentials for petechial rash and easy bruising apart from bleeding diathesis and vasculitis in the contemporary world, especially in at-risk populations.
Copyright © 2022, Amisha et al.

Entities:  

Keywords:  ascorbic acid; ascorbic acid deficiency; case report; rare case report; scurvy; vitamin c; vitamin c deficiency

Year:  2022        PMID: 35371727      PMCID: PMC8958866          DOI: 10.7759/cureus.22622

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  9 in total

1.  Fast-food consumption among US adults and children: dietary and nutrient intake profile.

Authors:  Sahasporn Paeratakul; Daphne P Ferdinand; Catherine M Champagne; Donna H Ryan; George A Bray
Journal:  J Am Diet Assoc       Date:  2003-10

Review 2.  The transport of vitamin C and effects of disease.

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Journal:  Proc Nutr Soc       Date:  1992-08       Impact factor: 6.297

3.  Micronutrient status in elderly people. Geriatrie/Min. Vit. Aux Network.

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Journal:  Int J Vitam Nutr Res       Date:  1996       Impact factor: 1.784

4.  Scurvy in the developed world.

Authors:  Alexa Smith; Gina Di Primio; Susan Humphrey-Murto
Journal:  CMAJ       Date:  2011-05-09       Impact factor: 8.262

Review 5.  Adult scurvy.

Authors:  J V Hirschmann; G J Raugi
Journal:  J Am Acad Dermatol       Date:  1999-12       Impact factor: 11.527

6.  Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003-2004 National Health and Nutrition Examination Survey (NHANES).

Authors:  Rosemary L Schleicher; Margaret D Carroll; Earl S Ford; David A Lacher
Journal:  Am J Clin Nutr       Date:  2009-08-12       Impact factor: 7.045

7.  Modern scurvy.

Authors:  Rian A A Wijkmans; Koen Talsma
Journal:  J Surg Case Rep       Date:  2016-01-10

Review 8.  Vitamin C and Heart Health: A Review Based on Findings from Epidemiologic Studies.

Authors:  Melissa A Moser; Ock K Chun
Journal:  Int J Mol Sci       Date:  2016-08-12       Impact factor: 5.923

Review 9.  Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review.

Authors:  Nicholas N DePhillipo; Zachary S Aman; Mitchell I Kennedy; J P Begley; Gilbert Moatshe; Robert F LaPrade
Journal:  Orthop J Sports Med       Date:  2018-10-25
  9 in total

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