Literature DB >> 35371706

Utility of Optical Coherence Tomography Angiography (OCTA) in Granulomatosis With Polyangiitis.

Salil Mehta1, Neena Chitnis2, Amey Medhekar3.   

Abstract

A 61-year-old male presented with visual loss in the left eye. A CT scan of the chest revealed multiple lung cavities in both lungs. He had a positive C-ANCA suggestive of granulomatosis with polyangiitis. There were multiple areas of superficial retinal opacification in the right eye and anterior ischemic optic neuropathy in the left eye. An optical coherence tomography (OCT)/optical coherence tomography angiography (OCTA) revealed areas of superficial capillary dropout and areas of flow void in the choriocapillaris. The patient underwent immunosuppressive therapy and at follow-up, there was a reduction in the flow voids. Use of the OCT/OCTA allowed us to detect clinically visible and occult retinal/choroidal ischemia/inflammation and monitor response.
Copyright © 2022, Mehta et al.

Entities:  

Keywords:  anterior ischemic optic neuropathy; immunosuppressive treatment; optical coherence angiography; retinal vasculitis; wegener's granulomatosis

Year:  2022        PMID: 35371706      PMCID: PMC8958215          DOI: 10.7759/cureus.22612

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  10 in total

1.  Central retinal artery occlusion and bilateral choroidal infarcts in Wegener's granulomatosis.

Authors:  S Mirza; A R Raghu Ram; B S Bowling; M Nessim
Journal:  Eye (Lond)       Date:  1999-06       Impact factor: 3.775

2.  Retinal and choroidal arterial occlusion in Wegener's granulomatosis.

Authors:  Tomohiro Iida; Richard F Spaide; Jeff Kantor
Journal:  Am J Ophthalmol       Date:  2002-01       Impact factor: 5.258

3.  Granulomatous choroiditis in Wegener granulomatosis.

Authors:  Alan D Proia
Journal:  Arch Ophthalmol       Date:  2011-04

Review 4.  Wegener's granulomatosis.

Authors:  L E Harman; C E Margo
Journal:  Surv Ophthalmol       Date:  1998 Mar-Apr       Impact factor: 6.048

5.  Granulomatosis with polyangiitis-associated ischemic optic neuropathy in a previously healthy 50-year-old female.

Authors:  Michael S Quist; Paramjit K Bhullar; Landon C Meekins; Divakar Gupta
Journal:  Am J Ophthalmol Case Rep       Date:  2020-09-15

6.  Choroidal granulomas visualized by enhanced depth imaging optical coherence tomography.

Authors:  Alessandro Invernizzi; Chiara Mapelli; Francesco Viola; Mario Cigada; Luca Cimino; Roberto Ratiglia; Giovanni Staurenghi; Amod Gupta
Journal:  Retina       Date:  2015-03       Impact factor: 4.256

Review 7.  Orbital granulomatosis with polyangiitis (Wegener granulomatosis): clinical and pathologic findings.

Authors:  Karra Muller; Jonathan H Lin
Journal:  Arch Pathol Lab Med       Date:  2014-08       Impact factor: 5.534

8.  Optical coherence tomography angiography for the diagnosis of granulomatosis with polyangiitis with serous retinal detachment: A case report.

Authors:  Noriko Takashi; Aya Nakamura; Keiko Kataoka; Yoshihiko Usui; Yasuki Ito; Hiroki Kaneko
Journal:  Medicine (Baltimore)       Date:  2021-02-19       Impact factor: 1.817

9.  Atypical painless vision loss in a patient with granulomatosis with polyangiitis.

Authors:  Patricia C Nelson; Vamsi Kunam; Claudia Prospero Ponce
Journal:  GMS Ophthalmol Cases       Date:  2020-12-15
  10 in total

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