| Literature DB >> 35363212 |
Pei-Chen Lin1,2, Nan-Chun Wu3, Hsiu-Chen Su3, Chien-Chin Hsu4,5, Kuo-Tai Chen4,6.
Abstract
ABSTRACT: The incidence of geriatric trauma is increasing due to the growing elderly population. Healthcare providers require a global perspective to differentiate critical factors that might alter patients' prognosis.We retrospectively reviewed all adult patients admitted to a trauma center during a 4-year period. We identified 655 adult trauma patients aged from 18 to 64 (nongeriatric group) and 273 trauma patients ≥65 years (geriatric group). Clinical data were collected and compared between the 2 groups.The geriatric group had a higher incidence of trauma and higher Injury Severity Scores than did the nongeriatric group. Fewer geriatric patients underwent surgical treatment (all patients: geriatric vs nongeriatric: 65.9% vs 70.7%; patients with severe trauma: geriatric vs nongeriatric: 27.6% vs 44.5%). Regarding prognosis, the geriatric group exhibited higher mortality rate and less need for long-term care (geriatric vs nongeriatric: mortality: 5.5% vs 1.8%; long-term care: 2.2% vs 5.0%).We observed that geriatric patients had higher trauma incidence and higher trauma mortality rate. Aging is a definite predictor of poor outcomes for trauma patients. Limited physiological reserves and preference for less aggressive treatment might be the main reasons for poor outcomes in elderly individuals.Entities:
Mesh:
Year: 2022 PMID: 35363212 PMCID: PMC9281953 DOI: 10.1097/MD.0000000000028913
Source DB: PubMed Journal: Medicine (Baltimore) ISSN: 0025-7974 Impact factor: 1.817
Figure 1Study profile. The number in each box represents the number of cases for each group.
Figure 2We discovered that the incidence of trauma increased with age (18–64 vs 65–74 vs 75–84 vs ≥ 85 years: 0.5/1000 vs 1.0/1000 vs 1.4/1000 vs 2.9/1000). Moreover, we observed an increase in mortality with age.
Comparison of the demographic characteristics between geriatric and nongeriatric groups for all adult patients with trauma.
| Geriatric (All patients) | Non-geriatric (All patients) | ||
| Case number (%) | 273 (29.4%) | 655 (70.6%) | |
| Average age (yr) | 76.3 ± 8.0 | 42.3 ± 14.4 | .000 |
| Sex (Male) | 58.6% | 59.8% | .726 |
| Charlson Comorbidity Index >0 | 28.6% | 25.5% | .333 |
| Locations of injury | |||
| Street | 51.3% | 49.5% | .492 |
| Factory/Farm/Mine | 15.0% | 16.3% | |
| Home | 12.8% | 15.3% | |
| Public places | 5.1% | 3.1% | |
| Others/ Unknown | 15.8% | 15.3% | |
| Mechanisms of injury | |||
| Traffic accident | 49.5% | 49.5% | .616 |
| Fall | 29.7% | 33.4% | |
| Crush | 7.7% | 9.2% | |
| Burn/Electricity | 5.9% | 4.6% | |
| Penetrating injury | 4.8% | 3.5% | |
| Asphyxia/Drowning | 1.8% | 3.1% | |
| Suicide | 0.7% | 0,8% | |
| Prehospital transport | |||
| Transport by EMTs | 44.0% | 49.6% | .107 |
| Transport by themselves | 30.4% | 30.7% | |
| Transfer from other hospital | 25.6% | 19.7% | |
| Time from injury to ED (median, interquartile range, min) | 47.0 (28.0–92.5) | 42.0 (25.0–80.0) | .005 |
| Vital signs at ED arrival | |||
| GCS | 14.3 ± 2.3 | 14.4 ± 2.0 | .196 |
| SAP (mm Hg) | 145.5 ± 32.3 | 144.9 ± 32.9 | .626 |
| HR (beat/min) | 85.1 ± 19.3 | 86.4 ± 19.2 | .874 |
| RR (respiration/min) | 17.3 ± 2.9 | 17.4 ± 2.4 | .022 |
| Temperature (°C) | 36.5 ± 0.6 | 36.5 ± 0.7 | .497 |
| Shock Index (HR/SAP) | 0.6 ± 0.2 | 0.6 ± 0.2 | .318 |
| Triage | |||
| Triage 1 | 7.7% | 7.8% | .873 |
| Triage 2 | 46.2% | 44.4% | |
| Triage 3 | 45.8% | 47.6% | |
| Triage 4 | 0.4% | 0.2% | |
| Injury regions (Abbreviated Injury Scale >2) | |||
| Head and neck | 22.7% | 20.9% | .114 |
| Face | 0.4% | 1.1% | |
| Chest | 7.7% | 9.2% | |
| Abdomen | 2.9% | 2.9% | |
| Extremity | 23.8% | 27.8% | |
| External | 1.8% | 0.3% | |
| Severity of trauma | |||
| RTS | 7.6603 ± 0.7588 | 7.6868 ± 0.6582 | .294 |
| ISS | 10.1 ± 10.7 | 9.2 ± 7.6 | .004 |
| NISS | 12.7 ± 12.6 | 11.5 ± 10.5 | .013 |
| TRISS | 0.9475 ± 0.1440 | 0.9571 ± 0.1251 | .087 |
| Laboratory tests | |||
| White cell count (cell/uL) | 11800 ± 4800 | 11400 ± 4600 | .178 |
| Hemoglobin (g/L) | 13.6 ± 2.0 | 13.4 ± 2.2 | .090 |
| Platelet (cell/uL) | 240700 ± 67700 | 242300 ± 71100 | .882 |
| PT (INR) | 1.0 ± 0.1 | 1.0 ± 0.1 | .518 |
| APTT (sec) | 25.9 ± 3.9 | 25.9 ± 3.3 | .803 |
| Sodium (mmol/L) | 139.0 ± 3.0 | 139.5 ± 2.5 | .738 |
| Potassium (mmol/L) | 3.8 ± 0.3 | 3.8 ± 0.4 | .034 |
| Glucose (g/L) | 140.7 ± 62.1 | 135.1 ± 48.5 | .012 |
| Creatinine (g/L) | 1.0 ± 0.9 | 1.0 ± 0.7 | .734 |
| Alanine transaminase (U/L) | 32.0 ± 56.6 | 32.6 ± 47.5 | .975 |
| Management and hospital course | |||
| Surgery | 65.9% | 70.7% | .000 |
| Time from ED to ward (median, interquartile range, min) | 40.5 (19.0–83.0) | 40.5 (20.0–75.5) | .380 |
| Time from ED to surgery (median, interquartile range, min) | 323.5 (211.3–746.8) | 347.0 (199.0–671.0) | .808 |
| Hospital stay (day) | 9.3 ± 10.9 | 8.2 ± 9.1 | .457 |
| ICU requirement | 22.3% | 16.9% | .054 |
| ICU stay (day) | 8.1 ± 12.6 | 7.5 ± 7.6 | .115 |
∗SAP = systolic arterial pressure
†HR = heart rate
‡RR = respiratory rate
§RTS = revised trauma score
¶ISS = Injury Severity Score, jNISS = New Injury Severity Score, ∗∗TRISS = Trauma Injury Severity Score, jjGCS = Glasgow Coma Scale, ∗∗∗EMS: emergency medical service, ≠ICU = intensive care unit.
Comparison of demographic characteristics between geriatric and nongeriatric groups for patients with severe trauma (Injury Severity Score >15).
| Geriatric (ISS > 15 patients) | Non-geriatric (ISS > 15 patients) | ||
| Case number (%) | 58 (31.2%) | 128 (68.8%) | |
| Average age (yr) | 76.1 ± 8.1 | 41.2 ± 14.5 | .000 |
| Sex (Male) | 65.5% | 65.5% | .989 |
| Charlson Comorbidity Index > 0 | 34.5% | 29.7% | .513 |
| Locations of injury | |||
| Street | 70.7% | 61.7% | .561 |
| Factory/ Farm/Mine | 6.9% | 9.4% | |
| Home | 12.1% | 10.2% | |
| Public places | 3.4% | 3.9% | |
| Others/ Unknown | 6.9% | 14.8% | |
| Mechanisms of injury | |||
| Traffic accident | 69.0% | 57.0% | .264 |
| Fall | 24.1% | 30.5% | |
| Others | 6.9% | 12.5% | |
| Prehospital transport | |||
| Transport by EMTs | 51.7% | 57.0% | .041 |
| Transport by themselves | 6.9% | 17.2% | |
| Transfer from other hospital | 41.4% | 25.8% | |
| Time from injury to ED (median, interquartile range, min) | 51.0 (26.5–164.0) | 37.0 (25.0–112.0) | .334 |
| Vital signs at ED arrival | |||
| GCS | 12.2 ± 4.3 | 12.8 ± 3.6 | .219 |
| SAP (mm Hg) | 146.7 ± 40.4 | 139.8 ± 39.9 | .891 |
| HR (beat/min) | 87.9 ± 24.3 | 90.6 ± 21.8 | .611 |
| RR (respiration/min) | 17.1 ± 4.7 | 17.5 ± 3.5 | .029 |
| Temperature (°C) | 36.5 ± 0.6 | 36.3 ± 0.9 | .783 |
| Shock Index (HR/SAP) | 0.6 ± 0.3 | 0.7 ± 0.3 | .363 |
| Triage | |||
| Triage 1 | 32.8% | 29.7% | .395 |
| Triage 2 | 55.2% | 50.0% | |
| Triage 3 | 12.1% | 20.3% | |
| Injury regions (Abbreviated Injury Scale >2) | |||
| Head and neck | 77.6% | 81.3% | .188 |
| Face | 1.7% | 3.9% | |
| Chest | 25.9% | 35.2% | |
| Abdomen | 8.6% | 7.0% | |
| Extremity | 8.6% | 16.4% | |
| External | 3.4% | 0.0% | |
| Severity of trauma | |||
| RTS | 7.0701 ± 1.4942 | 7.2367 ± 1.2989 | .211 |
| ISS | 25.2 ± 14.6 | 21.8 ± 7.0 | .000 |
| NISS | 32.2 ± 12.9 | 28.7 ± 9.7 | .036 |
| TRISS | 0.8094 ± 0.2716 | 0.8687 ± 0.2168 | .026 |
| Laboratory tests | |||
| White cell count (cell/uL) | 13800 ± 6400 | 12500 ± 5400 | .069 |
| Hemoglobin (g/L) | 13.2 ± 1.8 | 12.8 ± 2.4 | .043 |
| Platelet (cell/uL) | 209800 ± 67800 | 233100 ± 98000 | .324 |
| PT (INR) | 1.0 ± 0.1 | 1.0 ± 0.2 | .671 |
| APTT (sec) | 27.2 ± 7.9 | 26.2 ± 5.9 | .239 |
| Sodium (mmol/L) | 138.1 ± 4.2 | 139.5 ± 2.7 | .466 |
| Potassium (mmol/L) | 3.7 ± 0.4 | 3.7 ± 0.5 | .290 |
| Glucose (g/L) | 157.4 ± 60.1 | 153.7 ± 54.1 | .705 |
| Creatinine (g/L) | 1.4 ± 2.1 | 1.0 ± 0.5 | .002 |
| Alanine transaminase (U/L) | 56.4 ± 126.5 | 41.8 ± 43.6 | .028 |
| Management and hospital course | |||
| Surgery | 27.6% | 44.5% | .028 |
| Time from ED to ward (median, interquartile range, min) | 66.0 (23.0–164.0) | 56.0 (21.0–168.0) | .468 |
| Time from ED to surgery (median, interquartile range, min) | 408.5 (109.5–1552.3) | 355.0 (94.5–1328.0) | .805 |
| Hospital stay (day) | 10.2 ± 10.2 | 8.9 ± 10.5 | .931 |
| ICU requirement | 27.6% | 16.4% | .077 |
| ICU stay (day) | 6.8 ± 9.6 | 5.3 ± 4.2 | .166 |
∗SAP = systolic arterial pressure
†HR = heart rate
‡RR = respiratory rate
§RTS = Revised Trauma Score
¶ISS = Injury Severity Score, jNISS = New Injury Severity Score, ∗∗TRISS = Trauma Injury Severity Score, jjGCS = Glasgow Coma Scale, ∗∗∗EMS = emergency medical service, ≠ICU = intensive care unit.
Figure 3Regarding prognosis of the geriatric and nongeriatric groups, the geriatric group had a higher proportion of patients who died and lower proportion of patients who required long-term care. For all patients and for patients with severe trauma, the incidence rates of complications were comparable between geriatric and nongeriatric groups.
Data for all patients who underwent surgery. We observed that the geriatric group had a lower percentage of patients with multiple trauma than did the nongeriatric group, although the difference was nonsignificant. The geriatric group included fewer patients who sustained severe injuries in the head and neck regions (defined as Abbreviated Injury Scale of >2 for head and neck regions). Nevertheless, the geriatric group had a higher proportion of patients who died, required log-term care, and had complications.
| Geriatric (184) | Nongeriatric (465) | ||
| Multiple trauma† | 3.8% | 7.5% | .082 |
| Head and neck AIS‡ > 2 | 20.0% | 42.3% | .000 |
| Requirement for intensive care | 11.4% | 11.2% | .933 |
| Life-saving procedures∗ | 4.3% | 7.1% | .194 |
| Died | 3.8% | 1.3% | .000 |
| Long-term care | 9.8% | 1.7% | |
| Recovery | 85.9% | 95.9% | |
| Acute transfer | 0.5% | 1.1% | |
| Complications | 3.8% | 3.2% | .000 |
Patients whose Injury Severity Score was >2 in two regions.
Abbreviated Injury Scale.
Included emergent life-saving surgery and transarterial embolization.