Literature DB >> 353623

The effect of calcium dobesilate on nonproliferative diabetic retinopathy: a controlled study.

R L Stamper, M E Smith, S B Aronson, J C Cavender, G W Cleasby, W E Fung, B Becker.   

Abstract

Two independent, double-masked, controlled studies were made to evaluate the efficacy of calcium dobesilate for the treatment of nonproliferative diabetic retinopathy. Forty-two patients underwent a six-month crossover evaluation while receiving calcium dobesilate (750 mg per day) and placebo in random order. Thirty-six patients received calcium dobesilate (1,000 mg per day) or placebo for one year. Evaluation by clinical examination, fluorescein angiography, angiography, and fundus photography failed to demonstrate any beneficial effect of calcium dobesilate.

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Year:  1978        PMID: 353623     DOI: 10.1016/s0161-6420(78)35643-8

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  6 in total

1.  Effectiveness and cost-benefit analysis of intensive treatment and teaching programmes for type 1 (insulin-dependent) diabetes mellitus in Moscow--blood glucose versus urine glucose self-monitoring.

Authors:  E G Starostina; M Antsiferov; G R Galstyan; C Trautner; V Jörgens; U Bott; I Mühlhauser; M Berger; I I Dedov
Journal:  Diabetologia       Date:  1994-02       Impact factor: 10.122

2.  Effect of adding oral calcium dobesilate to laser photocoagulation on the macular thickness in patients with diabetic macular edema: a randomized clinical trial.

Authors:  Mostafa Feghhi; Fereydoun Farrahi; Mohammadreza Abbaspour; Akbar Takhtaeian
Journal:  Adv Pharm Bull       Date:  2014-08-10

3.  Calcium dobesilate inhibits the alterations in tight junction proteins and leukocyte adhesion to retinal endothelial cells induced by diabetes.

Authors:  Ermelindo C Leal; João Martins; Paula Voabil; Joana Liberal; Carlo Chiavaroli; Jacques Bauer; José Cunha-Vaz; António F Ambrósio
Journal:  Diabetes       Date:  2010-07-13       Impact factor: 9.461

Review 4.  Update on the Effects of Antioxidants on Diabetic Retinopathy: In Vitro Experiments, Animal Studies and Clinical Trials.

Authors:  Jose Javier Garcia-Medina; Elena Rubio-Velazquez; Elisa Foulquie-Moreno; Ricardo P Casaroli-Marano; Maria Dolores Pinazo-Duran; Vicente Zanon-Moreno; Monica Del-Rio-Vellosillo
Journal:  Antioxidants (Basel)       Date:  2020-06-26

5.  Efficacy and Safety of TangWang Prescription for Type 2 Non-Proliferative Diabetic Retinopathy: A Study Protocol for a Randomized Controlled Trial.

Authors:  Yuehong Zhang; Yuqing Zhang; Wenjing Huang; Xiang Meng; Fan Yang; Qi Bao; Meizhen Zhang; Yanan Yang; Qing Ni; Fengmei Lian; Xiaolin Tong
Journal:  Front Pharmacol       Date:  2021-03-15       Impact factor: 5.810

6.  Effect of Chinese Patent Medicines on Ocular Fundus Signs and Vision in Calcium Dobesilate-Treated Persons With Non-Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis.

Authors:  Yuehong Zhang; Xuedong An; Liyun Duan; Yingying Duan; Rongrong Zhou; Yuqing Zhang; Xiaomin Kang; Fengmei Lian
Journal:  Front Endocrinol (Lausanne)       Date:  2022-03-14       Impact factor: 5.555

  6 in total

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