Literature DB >> 35361133

Correction: Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study.

Isabelle Rydén1, Erik Thurin2, Louise Carstam2,3, Anja Smits2, Sasha Gulati4, Roger Henriksson5, Øyvind Salvesen6, Asgeir Store Jakola2,3,4.   

Abstract

Entities:  

Year:  2022        PMID: 35361133      PMCID: PMC8969255          DOI: 10.1186/s12885-022-09400-y

Source DB:  PubMed          Journal:  BMC Cancer        ISSN: 1471-2407            Impact factor:   4.430


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Correction to: BMC Cancer 21, 248 (2021) https://doi.org/10.1186/s12885-021-07939-w Following publication of the original article [1], an error was discovered in table 3 “Logistic regression model for use of antidepressants, sedatives and anti-epileptics, respectively, at one year following index date, for patients with LGG.” In this table, the numbers presented for anti-epileptics are equal to the numbers for the sedatives. There has been a copy error and numbers need to be adjusted. The new results do not change the conclusions. The updated table 3 is given below and the changed values are displayed in bold typeface. *p <0.05, **p < 0.01, ***p < 0.001
CovariateUnivariableMultivariable
OR (95 % CI)p-valueOR (95 % CI)p-value
ANTIDEPRESSANTS
 Index year (per year)1.22 (1.07-1.39)0.002**1.31 (1.11-1.55)0.002**
 Female (vs. male)2.99 (1.60-5.60)0.001**3.41 (1.71-6.80)0.001**
 Age (per year)1.02 (1.00-1.05)0.027*1.02 (1.00-1.05)0.11
 Income (per 100.000 SEK)0.96 (0.76-1.20)0.691.07 (0.83-1.39)0.60
 Higher education (vs. lower education)0.94 (0.78-1.15)0.560.97 (0.78-1.21)0.78
 History of depression7.61 (3.88-14.94)<0.001***6.12 (2.96-12.63)<0.001***
 Use of antidepressants preoperatively14.15 (5.88-34.08),<0.001***
 Elixhauser comorbidity index (0, 1, 2, >3)1.33 (0.96-1.84)0.091.09 (0.75-1.59)0.65
 Functional level (per WHO performance status category)0.98 (0.92-1.03)0.380.96 (0.88-1.06)0.42
 Tumour size (6)1.08 (0.96-1-21)0.220.92 (0.79-1.07)0.30
SEDATIVES
 Index year (per year)1.13 (0.99-1.29)0.071.12 (0.97-1.30)0.14
 Female (vs. male)1.23 (0.66-2.30)0.511.13 (0.58-2.19)0.73
 Age (per year)1.02 (1.00-1.04)0.091.02 (0.99-1.04)0.24
 Income (per 100.000 SEK)0.87 (0.67-1.13)0.300.90 (0.62-1.22)0.49
 Higher education (vs. lower education)0.81 (0.66-1.00)0.050.90 (0.71-1.13)0.35
 History of anxiety and/or sleeping difficulties2.58 (1.36-4.90)0.004**2.14 (1.09-4.20)0.027*
 use of sedatives preoperatively3.05 (1.60-5.82),<0.001***
 Elixhauser comorbidity index (0, 1, 2, >3)1.37 (0.98-1.92)0.071.17 (0.80-1.70)0.41
 Functional level (per WHO performance status category)0.97 (0.91-1.04)0.420.97 (0.89-1.05)0.43
 Tumour size (6)1.09 (0.97-1.23)0.171.00 (0.87-1.16)0.98
ANTI-EPILEPTICS
 Index year (per year)1.00 (0.92-1.08)1.001.01 (0.92-1.12)0.83
 Female (vs. male)1.11 (0.75-1.64)0.601.13 (0.71-1.82)0.60
 Age (per year)1.00 (0.98-1.01)0.641.00 (0.98-1.02)0.93
 Income (per 100.000 SEK)1.02 (0.88-1.18)0.790.94 (0.79-1.12)0.49
 Higher education (vs. lower education)1.04 (0.92-1.19)0.531.04 (0.87-1.23)0.69
 History of AED-use and/or seizure/epilepsy preoperatively12.16 (7.15-20.69)<0.001***12.98 (7.53-22.37)<0.001***
 Elixhauser comorbidity index (0, 1, 2, >3)0.90 (0.69-1.17)0.420.93 (0.67-1.28)0.64
 Functional level (per WHO performance status category)1.00 (0.99-1.01)0.851.00 (0.98-1.01)0.85
 Tumour size (6)1.03 (0.94-1.12)0.581.00 (0.90-1.13)0.94
 Biopsy vs resection0.78 (0.49-1.25)0.300.67 (0.38 –1.19)0.17

*p <0.05, **p < 0.01, ***p < 0.001

  1 in total

1.  Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study.

Authors:  Isabelle Rydén; Erik Thurin; Louise Carstam; Anja Smits; Sasha Gulati; Roger Henriksson; Øyvind Salvesen; Asgeir Store Jakola
Journal:  BMC Cancer       Date:  2021-03-08       Impact factor: 4.638

  1 in total

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