Zahra Jafari1, Thomas Copps2, Glenn Hole2, Femi Nyatepe-Coo2, Bryan E Kolb3, Majid H Mohajerani3. 1. Department of Neuroscience, Canadian Centre for Behavioural Neuroscience (CCBN), University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada. Zahra.jafari@uleth.ca. 2. Audiology First, Lethbridge, AB, T1J 4B5, Canada. 3. Department of Neuroscience, Canadian Centre for Behavioural Neuroscience (CCBN), University of Lethbridge, Lethbridge, AB, T1K 3M4, Canada.
Abstract
PURPOSE: Whereas chronic noise exposure (CNE) is a known risk factor for tinnitus, little is known about how a history of CNE impacts tinnitus characteristics and its comorbid symptoms. METHODS: Seventy-five participants with chronic tinnitus (59m/16f, 22-78 years, 48 with sensory-neural hearing loss, and 27 with a normal audiogram) including 43 individuals with (Tin-CNE group) and 32 without (Tin group) a history of long-term occupational noise exposure were studied. Tinnitus characteristics were rated by a visual analog scale, and tinnitus comorbid symptoms were scored using self-assessment questionnaires. RESULTS: The Tin-CNE group showed reduced uncomfortable loudness level (ULL), sound tolerance, and quality of life (QoL), and increased tinnitus loudness, tinnitus handicap, anxiety, depression, insomnia severity, and tinnitus annoyance scores compared to the Tin group. Higher tinnitus loudness and a lower anxiety score were observed in participants with hearing loss relative to those without. Using a stepwise regression model also showed that tinnitus-related characteristics, hyperacusis, and tinnitus comorbid symptoms enhance one another. CONCLUSIONS: The findings were in support of accumulative evidence indicating the adverse auditory and non-auditory effects of CNE, including exacerbated sound intolerance and tinnitus-related psychiatric symptoms. The results also showed that tinnitus alone can affect mental health regardless of hearing loss.
PURPOSE: Whereas chronic noise exposure (CNE) is a known risk factor for tinnitus, little is known about how a history of CNE impacts tinnitus characteristics and its comorbid symptoms. METHODS: Seventy-five participants with chronic tinnitus (59m/16f, 22-78 years, 48 with sensory-neural hearing loss, and 27 with a normal audiogram) including 43 individuals with (Tin-CNE group) and 32 without (Tin group) a history of long-term occupational noise exposure were studied. Tinnitus characteristics were rated by a visual analog scale, and tinnitus comorbid symptoms were scored using self-assessment questionnaires. RESULTS: The Tin-CNE group showed reduced uncomfortable loudness level (ULL), sound tolerance, and quality of life (QoL), and increased tinnitus loudness, tinnitus handicap, anxiety, depression, insomnia severity, and tinnitus annoyance scores compared to the Tin group. Higher tinnitus loudness and a lower anxiety score were observed in participants with hearing loss relative to those without. Using a stepwise regression model also showed that tinnitus-related characteristics, hyperacusis, and tinnitus comorbid symptoms enhance one another. CONCLUSIONS: The findings were in support of accumulative evidence indicating the adverse auditory and non-auditory effects of CNE, including exacerbated sound intolerance and tinnitus-related psychiatric symptoms. The results also showed that tinnitus alone can affect mental health regardless of hearing loss.
Authors: Dirk De Ridder; Winfried Schlee; Sven Vanneste; Alain Londero; Nathan Weisz; Tobias Kleinjung; Giriraj Singh Shekhawat; Ana Belén Elgoyhen; Jae-Jin Song; Gerhard Andersson; Divya Adhia; Andreia Aparecida de Azevedo; David M Baguley; Eberhard Biesinger; Ana Carolina Binetti; Luca Del Bo; Christopher R Cederroth; Rilana Cima; Jos J Eggermont; Ricardo Figueiredo; Thomas E Fuller; Silvano Gallus; Annick Gilles; Deborah A Hall; Paul Van de Heyning; Derek J Hoare; Eman M Khedr; Dimitris Kikidis; Maria Kleinstaeuber; Peter M Kreuzer; Jen-Tsung Lai; Jose Miguel Lainez; Michael Landgrebe; Lieber Po-Hung Li; Hubert H Lim; Tien-Chen Liu; Jose Antonio Lopez-Escamez; Birgit Mazurek; Aage R Moller; Patrick Neff; Christo Pantev; Shi Nae Park; Jay F Piccirillo; Timm B Poeppl; Josef P Rauschecker; Richard Salvi; Tanit Ganz Sanchez; Martin Schecklmann; Axel Schiller; Grant D Searchfield; Richard Tyler; Veronika Vielsmeier; Johan W S Vlaeyen; Jinsheng Zhang; Yiwen Zheng; Matteo de Nora; Berthold Langguth Journal: Prog Brain Res Date: 2021-02-01 Impact factor: 2.453
Authors: S Khalfa; S Dubal; E Veuillet; F Perez-Diaz; R Jouvent; L Collet Journal: ORL J Otorhinolaryngol Relat Spec Date: 2002 Nov-Dec Impact factor: 1.538