Purpose: The aim of this study was to report the presentation, treatment, and outcomes of vitreoretinal lymphoma (VRL) associated with hemorrhagic mass-like lesions (HMLs) in the retina. Methods: This study was a retrospective analysis of patients with HMLs associated with VRL seen at a single tertiary referral center. For each patient, the clinical charts, the fundus imaging, and the treatment outcomes were reviewed. Results: Three eyes of 2 patients had VRL with HMLs. In all study eyes, HMLs were preceded by an area of retinitis-like retinal infiltration and evolved into elevated hemorrhagic masses. Two eyes had multiple relapses with HMLs. All HMLs regressed with treatment and were replaced by extensive chorioretinal atrophy. Conclusion: VRL can present with HMLs. HMLs seem to correspond to massive intraretinal infiltration by VRL, mimicking a solid mass. Despite response to therapy, HMLs are associated with poor anatomical and functional outcomes.
Purpose: The aim of this study was to report the presentation, treatment, and outcomes of vitreoretinal lymphoma (VRL) associated with hemorrhagic mass-like lesions (HMLs) in the retina. Methods: This study was a retrospective analysis of patients with HMLs associated with VRL seen at a single tertiary referral center. For each patient, the clinical charts, the fundus imaging, and the treatment outcomes were reviewed. Results: Three eyes of 2 patients had VRL with HMLs. In all study eyes, HMLs were preceded by an area of retinitis-like retinal infiltration and evolved into elevated hemorrhagic masses. Two eyes had multiple relapses with HMLs. All HMLs regressed with treatment and were replaced by extensive chorioretinal atrophy. Conclusion: VRL can present with HMLs. HMLs seem to correspond to massive intraretinal infiltration by VRL, mimicking a solid mass. Despite response to therapy, HMLs are associated with poor anatomical and functional outcomes.
Authors: Lauren A Dalvin; Li-Anne S Lim; David Ancona-Lezama; Mehdi Mazloumi; Michael Chang; Pierluigi Porcu; Nina L Martinez; Jon Glass; Arman Mashayekhi; Carol L Shields Journal: Asia Pac J Ophthalmol (Phila) Date: 2020 Mar-Apr
Authors: Lauren A Dalvin; Li-Anne S Lim; David Ancona-Lezama; Mehdi Mazloumi; Michael Chang; Arman Mashayekhi; Carol L Shields Journal: Ophthalmol Retina Date: 2019-05-29
Authors: Maria Vittoria Cicinelli; Alessandro Marchese; Elisabetta Miserocchi; Chiara Giuffré; Luigi Berchicci; Giuseppe Querques; Francesco Bandello; Giulio Maria Modorati Journal: Ocul Immunol Inflamm Date: 2019-08-08 Impact factor: 3.070
Authors: Robert L Johnston; Adnan Tufail; Susan Lightman; Philip J Luthert; Carlos E Pavesio; Robert J Cooling; David Charteris Journal: Ophthalmology Date: 2004-03 Impact factor: 12.079