Literature DB >> 35355693

Adjuvant Treatment of Elderly Breast Cancer Patients: Offer the Best Chances of Cure.

Spyridon Marinopoulos1, Constantine Dimitrakakis1, Andreas Kalampalikis1, Flora Zagouri2, Angeliki Andrikopoulou2, Alexandros Rodolakis1.   

Abstract

Background: Breast cancer remains the most common cancer in women and a leading cause of death. Elderly people have a higher incidence of breast cancer since it increases with age. Furthermore, the extended life expectancy and advances in imaging techniques have led to an increased number of cases. Guidelines concerning the management of this specific age group are rare, mainly due to underrepresentation of seniors in clinical trials. Moreover, increased frailty, comorbidities, and a poor performance status make it complex to determine the best therapeutic approach. Summary: In this review, we attempt to summarize the current literature and aim to provide specific approaches and recommendations for prompt diagnosis, treatment, and management of breast cancer in the elderly. Key Messages: The establishment of applicable protocols is imperative and efforts are being made in this direction. A careful geriatric assessment and adequate consultation should be the standard of care and patient's preferences should always be considered.
Copyright © 2021 by S. Karger AG, Basel.

Entities:  

Keywords:  Age; Breast cancer; Disease management; Elderly patients

Year:  2021        PMID: 35355693      PMCID: PMC8914240          DOI: 10.1159/000513708

Source DB:  PubMed          Journal:  Breast Care (Basel)        ISSN: 1661-3791            Impact factor:   2.860


  100 in total

1.  Adjuvant paclitaxel and trastuzumab for node-negative, HER2-positive breast cancer.

Authors:  Sara M Tolaney; William T Barry; Chau T Dang; Denise A Yardley; Beverly Moy; P Kelly Marcom; Kathy S Albain; Hope S Rugo; Matthew Ellis; Iuliana Shapira; Antonio C Wolff; Lisa A Carey; Beth A Overmoyer; Ann H Partridge; Hao Guo; Clifford A Hudis; Ian E Krop; Harold J Burstein; Eric P Winer
Journal:  N Engl J Med       Date:  2015-01-08       Impact factor: 91.245

2.  Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement.

Authors:  Albert L Siu
Journal:  Ann Intern Med       Date:  2016-01-12       Impact factor: 25.391

3.  Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907.

Authors:  Stuart M Lichtman; Constance T Cirrincione; Arti Hurria; Aminah Jatoi; Maria Theodoulou; Antonio C Wolff; Julie Gralow; Daniel E Morganstern; Gustav Magrinat; Harvey Jay Cohen; Hyman B Muss
Journal:  J Clin Oncol       Date:  2016-01-11       Impact factor: 44.544

4.  A postal screening questionnaire in preventive geriatric care.

Authors:  J H Barber; J B Wallis; E McKeating
Journal:  J R Coll Gen Pract       Date:  1980-01

Review 5.  Tamoxifen with radiotherapy compared with Tamoxifen alone in elderly women with early-stage breast cancer treated with breast conserving surgery: A systematic review and meta-analysis.

Authors:  Tyler R Chesney; Jennifer Xin Yin; Nikoo Rajaee; Andrea C Tricco; Anthony W Fyles; Sergio A Acuna; Adena S Scheer
Journal:  Radiother Oncol       Date:  2017-04       Impact factor: 6.280

6.  Incidence of heart failure or cardiomyopathy after adjuvant trastuzumab therapy for breast cancer.

Authors:  Jersey Chen; Jessica B Long; Arti Hurria; Cynthia Owusu; Richard M Steingart; Cary P Gross
Journal:  J Am Coll Cardiol       Date:  2012-11-14       Impact factor: 24.094

7.  Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343.

Authors:  Kevin S Hughes; Lauren A Schnaper; Jennifer R Bellon; Constance T Cirrincione; Donald A Berry; Beryl McCormick; Hyman B Muss; Barbara L Smith; Clifford A Hudis; Eric P Winer; William C Wood
Journal:  J Clin Oncol       Date:  2013-05-20       Impact factor: 44.544

Review 8.  Impacts of geriatric evaluation and management programs on defined outcomes: overview of the evidence.

Authors:  L Z Rubenstein; A E Stuck; A L Siu; D Wieland
Journal:  J Am Geriatr Soc       Date:  1991-09       Impact factor: 5.562

Review 9.  Optimal sequence of adjuvant endocrine and radiation therapy in early-stage breast cancer - A systematic review.

Authors:  S F McGee; S Mazzarello; J M Caudrelier; M A G Lima; B Hutton; M Sienkiewicz; C Stober; R Fernandes; M F K Ibrahim; L Vandermeer; J Hilton; R Shorr; D Fergusson; M Clemons
Journal:  Cancer Treat Rev       Date:  2018-06-28       Impact factor: 12.111

10.  Delayed initiation of adjuvant chemotherapy in older women with breast cancer.

Authors:  Demetria Smith-Graziani; Xiudong Lei; Sharon H Giordano; Hui Zhao; Meghan Karuturi; Mariana Chavez-MacGregor
Journal:  Cancer Med       Date:  2020-08-07       Impact factor: 4.452

View more
  1 in total

Review 1.  Breast Cancer in Geriatric Patients: Current Landscape and Future Prospects.

Authors:  Hikmat Abdel-Razeq; Fawzi Abu Rous; Fawzi Abuhijla; Nayef Abdel-Razeq; Sarah Edaily
Journal:  Clin Interv Aging       Date:  2022-09-28       Impact factor: 3.829

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.