Literature DB >> 35355542

Pregnancy and Delivery Management With Recombinant Factor VIIa in a Glanzmann Thrombasthenia Patient: A Case Report.

Leonardo Enciso1,2, Rafael L Aragón-Mendoza3, Laura A León4, Carrie G Torres-Torres4.   

Abstract

The management of pregnancy and delivery in patients with Glanzmann thrombasthenia requires platelet transfusion and recombinant activated factor VII. We report two successful pregnancies in a single patient and propose a protocol for monitoring and treatment. The urgent need for controlled trials and other epidemiological studies is also underscored.
Copyright © 2022, Enciso et al.

Entities:  

Keywords:  glanzmann thrombasthenia; platelet refractoriness; platelet transfusion; pregnancy; recombinant activated factor vii

Year:  2022        PMID: 35355542      PMCID: PMC8957384          DOI: 10.7759/cureus.22570

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  7 in total

Review 1.  A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO.

Authors:  Paula H B Bolton-Maggs; Elizabeth A Chalmers; Peter W Collins; Paul Harrison; Stephen Kitchen; Ri J Liesner; Adrian Minford; Andrew D Mumford; Liakat A Parapia; David J Perry; Steve P Watson; Jonathan T Wilde; Michael D Williams
Journal:  Br J Haematol       Date:  2006-12       Impact factor: 6.998

2.  Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders.

Authors:  Elisa Civaschi; Catherine Klersy; Federica Melazzini; Nuria Pujol-Moix; Cristina Santoro; Marco Cattaneo; Cécile Lavenu-Bombled; Loredana Bury; Pietro Minuz; Paquita Nurden; Ana R Cid; Adam Cuker; Véronique Latger-Cannard; Remi Favier; Ilaria Nichele; Patrizia Noris
Journal:  Br J Haematol       Date:  2015-04-21       Impact factor: 6.998

Review 3.  A systematic review of the management and outcomes of pregnancy in Glanzmann thrombasthenia.

Authors:  S Siddiq; A Clark; A Mumford
Journal:  Haemophilia       Date:  2011-04-04       Impact factor: 4.287

Review 4.  Inherited platelet functional disorders: General principles and practical aspects of management.

Authors:  Adrienne Lee; Man-Chiu Poon
Journal:  Transfus Apher Sci       Date:  2018-07-19       Impact factor: 1.764

Review 5.  Glanzmann thrombasthenia: genetic basis and clinical correlates.

Authors:  Juliana Perez Botero; Kristy Lee; Brian R Branchford; Paul F Bray; Kathleen Freson; Michele P Lambert; Minjie Luo; Shruthi Mohan; Justyne E Ross; Wolfgang Bergmeier; Jorge Di Paola
Journal:  Haematologica       Date:  2020-03-05       Impact factor: 9.941

Review 6.  Glanzmann Thrombasthenia: Perspectives from Clinical Practice on Accurate Diagnosis and Optimal Treatment Strategies.

Authors:  Natalie Mathews; Georges-Etienne Rivard; Arnaud Bonnefoy
Journal:  J Blood Med       Date:  2021-06-11

7.  The Use of Recombinant Activated Factor VII in Patients with Glanzmann's Thrombasthenia.

Authors:  Man-Chiu Poon
Journal:  Thromb Haemost       Date:  2020-10-29       Impact factor: 5.249

  7 in total

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