Literature DB >> 35348952

Role of α7 Nicotinic Acetylcholine Receptors in Synaptic Transmission in Frog Neuromuscular Contacts.

O A Lenina1, I V Kovyazina2,3.   

Abstract

The role of α7 nicotinic acetylcholine receptors in coupling of synaptic activity and muscle contractions was studied in frog (Rana ridibunda) neuromuscular synapses. The amplitude of endplate currents, the probability of action potential generation, and the strength of muscle contractions decreased in the presence of selective α7 antagonist methyllycaconitine. The effects of nicotinic acetylcholine receptor blockade depended on the pattern of the motor nerve stimulation. It can be assumed that the muscle action potential is a factor of retrograde control of neurosecretion, which modulates activity of α7 nicotinic receptors and the release of acetylcholine from motor nerve endings.
© 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  acetylcholine; neuromuscular synapse; nicotinic cholinergic receptor

Mesh：

Substances：

Year:  2022        PMID： 35348952     DOI： 10.1007/s10517-022-05427-0

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  11 in total

Review 1.  Changing the tune: plasticity and adaptation of retrograde signals.

Authors:  Karl J Iremonger; Jaclyn I Wamsteeker Cusulin; Jaideep S Bains
Journal:  Trends Neurosci       Date:  2013-05-21       Impact factor: 13.837

Review 2.  Transsynaptic modulation of the synaptic vesicle cycle by cell-adhesion molecules.

Authors:  Kurt Gottmann
Journal:  J Neurosci Res       Date:  2008-02-01       Impact factor: 4.164

3.  Schwann cells sense and control acetylcholine spillover at the neuromuscular junction by α7 nicotinic receptors and butyrylcholinesterase.

Authors:  Konstantin A Petrov; Emmanuelle Girard; Alexandra D Nikitashina; Cesare Colasante; Véronique Bernard; Leniz Nurullin; Jacqueline Leroy; Dmitry Samigullin; Omer Colak; Evgenii Nikolsky; Benoit Plaud; Eric Krejci
Journal:  J Neurosci       Date:  2014-09-03       Impact factor: 6.167

Review 4.  Reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors through a highly conserved cysteine near the intracellular mouth of the channel: implications for diseases that involve oxidative stress.

Authors:  Arjun Krishnaswamy; Ellis Cooper
Journal:  J Physiol       Date:  2011-10-03       Impact factor: 5.182

5.  Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.

Authors:  H Tsuneki; R Klink; C Léna; H Korn; J P Changeux
Journal:  Eur J Neurosci       Date:  2000-07       Impact factor: 3.386

Review 6.  Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system.

Authors:  Jian-xin Shen; Jerrel L Yakel
Journal:  Acta Pharmacol Sin       Date:  2009-05-18       Impact factor: 6.150

7.  Rapid activation of presynaptic nicotinic acetylcholine receptors by nerve-released transmitter.

Authors:  Marc Rogers; Peter B Sargent
Journal:  Eur J Neurosci       Date:  2003-12       Impact factor: 3.386

8.  Mitochondrial reactive oxygen species inactivate neuronal nicotinic acetylcholine receptors and induce long-term depression of fast nicotinic synaptic transmission.

Authors:  Verónica A Campanucci; Arjun Krishnaswamy; Ellis Cooper
Journal:  J Neurosci       Date:  2008-02-13       Impact factor: 6.167

9.  A Novel Striated Muscle-Specific Myosin-Blocking Drug for the Study of Neuromuscular Physiology.

Authors:  Dante J Heredia; Douglas Schubert; Siddhardha Maligireddy; Grant W Hennig; Thomas W Gould
Journal:  Front Cell Neurosci       Date:  2016-12-01       Impact factor: 5.505

10.  A novel synaptic plasticity rule explains homeostasis of neuromuscular transmission.

Authors:  Gilles Ouanounou; Gérard Baux; Thierry Bal
Journal:  Elife       Date:  2016-05-03       Impact factor: 8.140
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.