| Literature DB >> 35347585 |
Parya Amini1, Mehran Amrovani2, Zohre Saleh Nassaj3, Parisa Ajorlou4, Aiyoub Pezeshgi5, Bahareh Ghahrodizadehabyaneh6.
Abstract
Preeclampsia (PE) is one of the complications, that threatens pregnant mothers during pregnancy. According to studies, it accounts for 3-7% of all pregnancies, and also is effective in preterm delivery. PE is the third leading cause of death in pregnant women. High blood pressure in PE can increase the risk of developing cardiovascular disease (CVD) in cited individuals, and is one of the leading causes of death in PE individuals. Atrial natriuretic peptide (ANP), Renin-Angiotensin system and nitric oxide (NO) are some of involved factors in regulating blood pressure. Therefore, by identifying the signaling pathways, that are used by these molecules to regulate and modulate blood pressure, appropriate treatment strategies can be provided to reduce blood pressure through target therapy in PE individuals; consequently, it can reduce CVD risk and mortality.Entities:
Keywords: Cardiovascular disease; Hypertension; Mechanism; Preeclampsia
Mesh:
Year: 2022 PMID: 35347585 DOI: 10.1007/s12012-022-09734-w
Source DB: PubMed Journal: Cardiovasc Toxicol ISSN: 1530-7905 Impact factor: 3.231