| Literature DB >> 3534636 |
E S Corp, S C Woods, D Porte, D M Dorsa, D P Figlewicz, D G Baskin.
Abstract
In vitro autoradiography and computer video densitometry were used to localize and quantify binding of 125I-insulin in the hypothalamus of the rat brain. Highest specific binding was found in the arcuate, dorsomedial, suprachiasmatic, paraventricular and periventricular regions. Significantly lower binding was present in the ventromedial nucleus and median eminence. The results are consistent with the hypothesis that insulin modulates the neural regulation of feeding by acting at sites in the hypothalamus.Entities:
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Year: 1986 PMID: 3534636 DOI: 10.1016/0304-3940(86)90430-1
Source DB: PubMed Journal: Neurosci Lett ISSN: 0304-3940 Impact factor: 3.046