Literature DB >> 35340253

Neuronal Apoptosis in Patients with Liver Cirrhosis and Neuronal Epileptiform Discharge Model Based upon Multi-Modal Fusion Deep Learning.

Nannan Chi1, Xiuping Wang2, Yun Yu3, Manman Wu4, Jianan Yu2.   

Abstract

Neurons refer to nerve cells. Each neuron is connected with thousands of other neurons to form a corresponding functional area and carry out complex communication with other functional areas. Its importance to the human body is self-evident. There are also many scholars studying the mechanism of apoptosis. This paper proposes a study of neuronal apoptosis in patients with liver cirrhosis and neuronal epileptiform discharge models based on multi-modal fusion deep learning, aiming to study the influencing factors of abnormal neuronal discharge in the brain. The method in this paper is to study multi-modal information fusion methods, perform Bayesian inference, and analyze multi-modal medical data. The function of these research methods is to obtain the relationship between the independence of information and the intersection of information among modalities. In the neuronal epileptiform discharge model, the mRNA expression level of the necroptotic signaling pathway related protein was detected, and the mechanism of neuronal necrosis in patients with liver cirrhosis was explored. Experiments show that the neuron recognition rate has been increased from 67.2% to 84.5%, and the time has been reduced, proving the effectiveness of deep learning.
Copyright © 2022 Nannan Chi et al.

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Year:  2022        PMID: 35340253      PMCID: PMC8947874          DOI: 10.1155/2022/2203737

Source DB:  PubMed          Journal:  J Healthc Eng        ISSN: 2040-2295            Impact factor:   2.682


  18 in total

Review 1.  Multifaceted roles of nitric oxide in the lateral geniculate nucleus: from visual signal transduction to neuronal apoptosis.

Authors:  C Nucci; L Morrone; L Rombolà; R Nisticò; S Piccirilli; L Cerulli
Journal:  Toxicol Lett       Date:  2003-04-04       Impact factor: 4.372

2.  Deep Leaning Based Multi-Modal Fusion for Fast MR Reconstruction.

Authors:  Lei Xiang; Yong Chen; Weitang Chang; Yiqiang Zhan; Weili Lin; Qian Wang; Dinggang Shen
Journal:  IEEE Trans Biomed Eng       Date:  2018-11-29       Impact factor: 4.538

3.  AMPAR-mediated Interictal Discharges in Neurons of Entorhinal Cortex: Experiment and Model.

Authors:  A V Chizhov; D V Amakhin; A V Zaizev; L G Magazanik
Journal:  Dokl Biol Sci       Date:  2018-05-22

4.  Low-intensity ultrasound suppresses low-Mg2+-induced epileptiform discharges in juvenile mouse hippocampal slices.

Authors:  Zhen Zhang; Weibao Qiu; Haiqing Gong; Guofeng Li; Qiuju Jiang; Peiji Liang; Hairong Zheng; Puming Zhang
Journal:  J Neural Eng       Date:  2019-02-28       Impact factor: 5.379

5.  Closed-loop feedback control and bifurcation analysis of epileptiform activity via optogenetic stimulation in a mathematical model of human cortex.

Authors:  Prashanth Selvaraj; Jamie W Sleigh; Heidi E Kirsch; Andrew J Szeri
Journal:  Phys Rev E       Date:  2016-01-26       Impact factor: 2.529

6.  Exendin-4 Enhances Motor Function Recovery via Promotion of Autophagy and Inhibition of Neuronal Apoptosis After Spinal Cord Injury in Rats.

Authors:  Hao-Tian Li; Xing-Zhang Zhao; Xin-Ran Zhang; Gang Li; Zhi-Qiang Jia; Ping Sun; Ji-Quan Wang; Zhong-Kai Fan; Gang Lv
Journal:  Mol Neurobiol       Date:  2015-07-22       Impact factor: 5.590

7.  Comparison of MR-PWI quantitative and semi-quantitative parameters for the evaluation of liver fibrosis.

Authors:  Ke Ding; Manrong Liu; Xue Wei; Ruisui Huang; Jiong Chen; Shanjin Lu; Dacheng Wang; Wei Lu
Journal:  BMC Med Imaging       Date:  2021-01-06       Impact factor: 1.930

8.  Aldehyde dehydrogenase 2 overexpression inhibits neuronal apoptosis after spinal cord ischemia/reperfusion injury.

Authors:  Xing-Zhen Liu; Xin Sun; Kang-Ping Shen; Wen-Jie Jin; Zhi-Yi Fu; Hai-Rong Tao; Zhi-Xing Xu
Journal:  Neural Regen Res       Date:  2017-07       Impact factor: 5.135

9.  Spine Medical Image Segmentation Based on Deep Learning.

Authors:  Qingfeng Zhang; Yun Du; Zhiqiang Wei; Hengping Liu; Xiaoxia Yang; Dongfang Zhao
Journal:  J Healthc Eng       Date:  2021-12-15       Impact factor: 2.682

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