Uterine Tumor Resembling Ovarian Sex Cord Tumors (UTROSCT): Two Case Reports of the Rare Uterine Neoplasm with Literature Review.

INTRODUCTION: Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare neoplasms with unknown etiology. This type of tumor has low malignant potential and mostly manifests as a benign clinical course.
MATERIALS AND METHODS: This article analyzes the case data, clinical manifestations, and histopathological characteristics of two cases of UTROSCT, and reviews the relevant literature. The diagnosis of UTROSCT is mainly based on histopathological examination. The histological characteristics of granulosa and Sertoli cell tumours are similar to the ovary under the microscope. These cases' clinical and radiological (MRI) findings have also been discussed.
RESULTS: The sex cord components are mixed in different proportions. The immunohistochemistry is diverse and can express sex cord markers together with both epithelial and smooth muscle markers. Both two cases revealed the signs of intratumoral cystic degeneration, intratumoral hemorrhage, and necrosis under MRI. These MRI features were helpful to prompt UTROSCT, which is histologically similar to granular cell tumors and is conducive to the differential diagnosis.
CONCLUSION: The current recommended treatment is total hysterectomy, but its biological behavior is not yet clear, and long-term follow-up is needed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.